The in situ preparation and trapping of chlorine azide provided a versatile one-pot method
for the azidochlorination of alkenes. Gaseous ClN3 generated from sodium azide …

The HKR of racemic anti-or syn-3-substituted epoxy esters catalyzed by a Co (III) salen
complex provides ready access to the corresponding enantioenriched 3, 4-disubstituted γ …

An efficient and facile approach for tetrachlorosilane as an in situ mediated transformation
via a one-pot, synthesis of vicinal bromoazides through the generation of BrN 3 from …

A short and efficient enantioselective synthesis of natural product (S)-3-hydroxypiperidine
has been achieved starting from commercially available raw materials employing two …

An efficient formal synthesis of (2S, 4R)-4-hydroxypipecolic acid has been achieved in high
optical purity (99% ee) from readily available benzaldehyde. The strategy employs an iodine …

An efficient synthesis of the 2, 3-disubstituted piperidines (+)-L-733,060 and (2S, 3S)-3-
hydroxypipecolic acid (≥ 99% ee) in high optical purity from commercially available starting …

A simple and highly efficient approach to an enantioenriched 2, 6‐disubstituted piperidin‐3‐
ol skeleton is developed from an aldehyde as a starting material by using organocatalytic …

Organic azides are placed in the interphase between chemistry, biology, medicine, and
materials science. Their uses in peptide chemistry, combinatorial chemistry, and the …

An enantiopure piperidine, a key intermediate for the synthesis of (+)-tofacitinib, has been
achieved in high optical purity (98% ee) from readily available crotyl alcohol. The key steps …

Several synthetic efforts are reported towards the optically active (−)-prosophylline and (+)-
prosophylline, and their derivatives. Interestingly and surprisingly, although only a few …