Recent Progress in Polyion Complex Nanoparticles with Enhanced Stability for Drug Delivery

X Ma, T Zhao, X Ren, H Lin, P He - Polymers, 2024 - mdpi.com
Polyion complex (PIC) nanoparticles, including PIC micelles and PICsomes, are typically
composed of poly (ethylene glycol) block copolymers coupled with oppositely charged …

[HTML][HTML] DNA polymer conjugates: Revolutionizing neurological disorder treatment through targeted drug delivery

P Panda, SS Kar, R Mohapatra - Next Materials, 2025 - Elsevier
Neurological disorders present a formidable challenge to modern medicine due to their
complex etiology and limited treatment options. Traditional therapeutic approaches often …

[HTML][HTML] Evaluation of Cytotoxicity and Metabolic Profiling of Synechocystis sp. Extract Encapsulated in Nano-Liposomes and Nano-Niosomes Using LC-MS …

L Azmy, IBM Ibraheem, SA Alsalamah, MI Alghonaim… - Biology, 2024 - mdpi.com
Simple Summary Cancer is the second leading cause of death worldwide, warranting the
development of safer, more effective therapies. Liposomes and niosomes can be considered …

Impact of Copolymer Architecture on Demicellization and Cargo Release via Head-to-Tail Depolymerization of Hydrophobic Blocks or Branches

C Gioldasis, A Gkamas, C Vlahos - Polymers, 2024 - mdpi.com
Utilizing molecular dynamics simulations, we explored the demicellization and cargo
release dynamics of linear and miktoarm copolymers, featuring one, two, and three …

Coacervation for biomedical applications: innovations involving nucleic acids

K Mirlohi, WCB McTigue - Soft Matter, 2025 - pubs.rsc.org
Gene therapies, drug delivery systems, vaccines, and many other therapeutics, although
seeing breakthroughs over the past few decades, still suffer from poor stability …

Brain targeted polymeric micelles as drug carriers for ischaemic stroke treatment

Z Zhao, H Song, M Qi, Y Liu, Y Zhang, S Li… - Journal of Drug …, 2024 - Taylor & Francis
Ischaemic stroke is a central nervous system disease with high morbidity, recurrence and
mortality rates. Thrombolytic and neuroprotective therapies are the main therapeutic …

Is it Time for Multi‐Drug Therapy with Combination of Therapeutic Nucleic Acids?

ZJ Leśnikowski - ChemMedChem, 2025 - Wiley Online Library
Therapeutic nucleic acids (TNAs) are a new class of drugs that exhibit different properties
and mechanisms of action from those of small molecules or biological drugs. Over twenty …

纳米药物递送系统体内命运分析新方法与新技术研究进展

王心怡, 付淑军, 孟祥骏, 吴伟, 顾景凯 - 药学进展, 2024 - pps.cpu.edu.cn
纳米药物递送系统(NDDSs) 能够改善药物的药代动力学行为, 将活性药物成分靶向递送至病灶,
并控制药物释放. 近年来, 随着纳米技术的快速发展, NDDSs 在医药领域展现出巨大潜力 …

Možnosti solubilizace antioxidačních látek

L Matošková - 2024 - digilib.k.utb.cz
Antioxidanty hrají zásadní úlohu při prevenci procesu stárnutí pokožky způsobeného vlivem
oxidativního stresu a celkově přispívají ke zdraví lidského organismu. V rámci předložené …

[引用][C] Therapeutic mRNAs for cancer immunotherapy: From structure to delivery

M Vishwakarma, W Akram, T Haider - 2024 - Elsevier