The F-box domain, so called after a conserved domain found in human cyclin F (5), was
described in 1996 (6) after first being denoted a conserved N-terminal domain found in a …

Mercury (Hg) exposure remains a major public health concern due to its widespread
distribution in the environment. Organic mercurials, such as MeHg, have been extensively …

Using synchrotron x-ray fluorescence mapping, we have examined the uptake and
localization of organic mercury in zebrafish larvae. Strikingly, the greatest accumulation of …

Background n-Butanol and isobutanol produced from biomass-derived sugars are promising
renewable transport fuels and solvents. Saccharomyces cerevisiae has been engineered for …

Fusarium head blight is a destructive disease of small grains. The disease is predominantly
caused by the haploid ascomycete fungus Fusarium graminearum in North America. To …

Many large molecular machines are too elaborate to assemble spontaneously and are built
through ordered pathways orchestrated by dedicated chaperones. During assembly of the …

Exposure to methylmercury causes severe damage to various tissues and organs in
humans. Although a variety of fluorescent chemosensors have been exploited, only few …

Methylmercury is an environmental pollutant that causes neurotoxicity. Recent studies have
reported that the ubiquitin-proteasome system is involved in defense against methylmercury …

The unfolded protein response (UPR) detects and mitigates the harmful effects of
dysregulated endoplasmic reticulum (ER) function. The UPR has been best characterized as …

We have previously demonstrated that the overexpression of enzymes involved in the
production of pyruvate, enolase 2 (Eno2) and D-lactate dehydrogenase (Dld3) renders yeast …