[HTML][HTML] Synthesis, kinetic studies, and QSAR of dinucleoside polyphosphate derivatives as human AK1 inhibitors
A Kozakiewicz-Piekarz, M Grzegórska… - Bioorganic …, 2024 - Elsevier
Adenylate kinase (AK) plays a crucial role in the metabolic monitoring of cellular adenine
nucleotide homeostasis by catalyzing the reversible transfer of a phosphate group between …
nucleotide homeostasis by catalyzing the reversible transfer of a phosphate group between …
Global profiling of arginine reactivity and ligandability in the human proteome
G Li, Y Wang, S Xie, T Hu, L Zhu, Y Zhai, Y Li, C Xu… - 2024 - researchsquare.com
Covalent small molecules targeting nucleophilic amino acids have emerged as a rapidly
advancing frontier in covalent drug development, with a primary focus on cysteine and lysine …
advancing frontier in covalent drug development, with a primary focus on cysteine and lysine …
Análisis computacional de la interacción entre estatinas y la isoenzima I de la adenilato quinasa humana (hAK1): evaluación de los sitios alostéricos y estimación de …
WJ Herrera Aranda, A Morales, M Bedoya Tabares - 2023 - dspace.utalca.cl
Las estatinas como fármacos inhiben de manera muy eficaz la enzima 3-hidroxi-3-metil-
glutaril-coenzima A reductasa (HMG-CoA reductasa) que cataliza el paso limitante de la …
glutaril-coenzima A reductasa (HMG-CoA reductasa) que cataliza el paso limitante de la …