Publisher Summary At fertilization in mammals, the incoming sperm makes two essential
contributions to the development of the new organism. One contribution is the DNA and all …

Blocks to polyspermic fertilization are necessary to prevent the incorporation of two sperm
nuclei into a zygote's genome, which would result in abnormal development. Many …

The first edition of the Textbook of Assisted Reproductive Techniques was published in
2001. As the textbook now enters its sixth edition, some 45 years since the birth of Louise …

Preliminary experiments carried out on ovine oocytes were designed to establish
correlations between activation protocols and subsequent rates of embryonic development …

We have examined the response of bovine oocytes matured in vitro for 24 hr to
parthenogenic activation using compounds that increase intracellular calcium (ionomycin) or …

In this study, we analysed the distribution of β tubulins to detect spindle and cytoplasmic
microtubules, α acetylated tubulins for sperm microtubules and chromatin configuration in …

This research was undertaken to improve development of parthenogenetic embryos
following various combined treatments of ethanol and cycloheximide. In Experiment 1 in …

OBJECTIVE: To evaluate efficiency of Ionomycin on fertilization and cleavage rates, embryo
development, and pregnancy rate after intracytoplasmic sperm injection (ICSI) in …

Egg activation in mammals is caused by cytosolic Ca 2+ oscillations that are essential for
development. However, despite increasing knowledge about signal transduction …

The objective of the present study was to examine the activity changes in histone H1 kinase
(also known as maturation-promoting factor [MPF]) and mitogen-activated protein kinase …