Hashimoto's thyroiditis (HT) is part of a spectrum of thyroid autoimmune conditions and this
review provides an update on the latest developments in the field. HT has a genetic …

Vitamin D is a steroid hormone traditionally connected to phosphocalcium metabolism. The
discovery of pleiotropic expression of its receptor and of the enzymes involved in its …

In spite of the advancements in understanding the pathogenic mechanisms of Graves'
disease (GD), its ultimate cause remains elusive. The majority of investigators agree that GD …

Background The triggering of thyroid autoimmunity in the genetically susceptible remains a
conundrum. Environmental exposures during gestation and/or early postnatally have …

Context: The pathogenesis of autoimmune Addison's disease (AAD) is thought to be due to
interplay of genetic, immune, and environmental factors. A month-of-birth effect, with …

Celiac disease (CD) is an immune-mediated systemic disorder induced by a trigger factor in
genetically susceptible individuals. There is emerging evidence about the impact of the …

Background: Environmental and genetic factors possibly trigger thyroid autoimmunity.
Studies on perinatal risk factors for childhood thyroid autoimmunity are sparse. Objectives …

Background The aim of this study was to analyze the seasonal birth month pattern in young
patients with autoimmune thyroiditis and compare it with youth controls. Methods Medical …

Background Season of birth, an exogenous indicator of early life environment, has been
linked with a higher risk of adverse health outcomes such as autoimmune thyroiditis …

Autoimmune thyroid disease (AITD) is characterised by the development of thyroid
autoantibodies, mainly anti-thyroid peroxidase antibodies, anti-thyroglobulin antibodies …