The meaning of the word mitochondrion (from the Greek mitos, meaning thread, and
chondros, grain) illustrates that the heterogeneity of mitochondrial morphology has been …

Abstract Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous group of
disorders sharing the same clinical phenotype, characterized by distal limb muscle wasting …

Peripheral nerves have peculiar energetic requirements because of considerable length of
axons and therefore correct mitochondria functioning and distribution along nerves is …

Abstract Introduction Mutations in GDAP1 (Ganglioside-induced differentiation-associated
protein 1) gene are linked to Charcot-Marie-Tooth disease (CMT), a Heterogenous group of …

Mutations in GDAP1, the ganglioside-induced differentiation-associated protein 1 gene,
cause Charcot–Marie–Tooth (CMT) type 4A, a severe autosomal recessive form of …

Impaired axonal transport has been postulated to play a role in the pathophysiology of
multiple neurodegenerative disorders. In this report, we describe the results of clinical and …

First described at the end of the nineteenth century by French neurologists Jean Martin
Charcot and Pierre Marie and British neurologist Howard Henry Tooth, Charcot-Marie-Tooth …

Abstract Charcot–Marie–Tooth disease (CMT) is the most frequent form of inherited
neuropathy with great variety of phenotypes, inheritance patterns, and causative genes …

Summary Charcot‐Marie‐Tooth disease (CMT) is the most common neuromuscular
disorder. It represents a group of clinically and genetically heterogeneous inherited …

Recent research in the field of inherited peripheral neuropathies (IPNs) such as Charcot–
Marie–Tooth (CMT) disease has helped identify the causative genes provided better …