Introduction Inhaled nitric oxide (iNO) is an important therapy for acute respiratory distress
syndrome (ARDS), pulmonary hypertension and pediatric hypoxemic respiratory failure …

Acute kidney injury (AKI) is associated with increased morbidity, prolonged hospitalization,
and mortality, especially in high risk patients. Phosphodiesterase 5 inhibitors (PDE5Is) …

The pathogenesis understanding of SARS-CoV-2 infection is crucial to prevent the rampant
spread of COVID-19 and its contribution to deterioration in health, even death. Nitric oxide …

The use of gentamicin (GM) is limited due to its nephrotoxicity mediated by oxidative stress.
This study aimed to evaluate the capacity of a flavonoid-rich extract of Sambucus nigra L …

Background and purpose: Gentamicin (GM) is used against bacterial infections. The aim of
our investigation was to evaluate the role of inflammation and also oxidative damage in …

Epilepsy is one of the furthermost common neurodegenerative diseases affecting above 50
million individuals worldwide. The pathogenesis of epileptic seizures is not satisfactorily …

Diclofenac, one of the most commonly used non-steroidal anti-inflammatory drugs, leads to
severe adverse effects on the kidneys. The aim of the present study was to investigate the …

Gentamicin (GNT) is a potent aminoglycoside antibiotic widely used to treat life-threatening
bacterial infections. We aim to investigate the potential protective effect of ursodeoxycholic …

Sildenafil and febuxostat protect against doxorubicin-induced nephrotoxicity; however the
exact mechanism remains to be elucidated. The effect of sildenafil and febuxostat on …

Chronic kidney disease (CKD) represents a worldwide health problem. Traditionally, the
nephroprotective treatment for CKD aims to slow progression to end-stage renal disease …