Bioactive peptides: From basic research to clinical trials and commercialization

P Duffuler, KS Bhullar… - Journal of agricultural …, 2022 - ACS Publications
Chronic diseases, including metabolic diseases, have become a worldwide public health
issue. Research regarding the use of bioactive peptides or protein hydrolysates derived from …

Antioxidant stress and anti-inflammatory activities of egg white proteins and their derived peptides: a review

N Zhou, Y Zhao, Y Yao, N Wu, M Xu, H Du… - Journal of agricultural …, 2021 - ACS Publications
Oxidative stress and chronic inflammation are the common pathological bases of chronic
diseases such as atherosclerosis, cancer, and cardiovascular diseases, but most of the …

Ellagic acid alleviates hepatic oxidative stress and insulin resistance in diabetic female rats

SA Polce, C Burke, LM França, B Kramer, AMA Paes… - Nutrients, 2018 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) affects more than 70% of patients with type 2
diabetes mellitus (T2DM) and has become one of the most common metabolic liver diseases …

[HTML][HTML] Trends and applications of food protein-origin hydrolysates and bioactive peptides

YHS Wu, YC Chen - Journal of Food and Drug Analysis, 2022 - ncbi.nlm.nih.gov
It was reported that protein hydrolysates or derived peptides have more functionalities than
their parent protein. Most functional protein hydrolysates or peptides are identified from …

Egg-derived peptides and hydrolysates: a new bioactive treasure for cardiometabolic diseases

S Moreno-Fernández, M Garcés-Rimón… - Trends in Food Science & …, 2020 - Elsevier
Background: Structure and function of egg proteins have been widely studied and, probably
because of its protein diversity and its different physiochemical properties, they have …

Health functions of egg protein

R Matsuoka, M Sugano - Foods, 2022 - mdpi.com
Egg protein is a remarkably abundant source of protein, with an amino acid score of 100 and
the highest net protein utilization rate. However, there have been relatively fewer studies …

An egg white-derived peptide enhances systemic insulin sensitivity and modulates markers of non-alcoholic fatty liver disease in obese, insulin resistant mice

SC de Campos Zani, R Wang, H Veida-Silva… - Metabolites, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic
syndrome, is a global health problem. Currently, no pharmacological treatment is approved …

Ovalbumin hydrolysates enhance skeletal muscle insulin-dependent signaling pathway in high-fat diet-fed mice

N Elhadad, SC de Campos Zani… - Journal of Agricultural …, 2024 - ACS Publications
Egg white hydrolysates (EWH) and ovotransferrin-derived peptides have distinct beneficial
effects on glucose metabolism. This research aims to investigate whether ovalbumin …

IRW (Isoleucine–Arginine–Tryptophan) Improves Glucose Tolerance in High Fat Diet Fed C57BL/6 Mice via Activation of Insulin Signaling and AMPK Pathways in …

SC de Campos Zani, M Son, KS Bhullar, CB Chan… - Biomedicines, 2022 - mdpi.com
IRW (Isoleucine–Arginine–Tryptophan), has antihypertensive and anti-inflammatory
properties in cells and animal models and prevents angiotensin-II-and tumor necrosis factor …

The alteration of gut microbiota by bioactive peptides: A review

Z Guo, D Yi, B Hu, Y Shi, Y Xin, Z Gu, H Liu… - Systems Microbiology …, 2021 - Springer
Evidences suggest that the homeostasis of gut microbiota is among the most important
factors for maintaining the physical and mental health of the host. Among the multiple factors …