Characteristics of animal models for COVID‐19
F Qi, C Qin - Animal Models and Experimental Medicine, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of
coronavirus disease 2019 (COVID‐19), the most consequential pandemic of this century …
coronavirus disease 2019 (COVID‐19), the most consequential pandemic of this century …
Differences in incidence, nature of symptoms, and duration of long COVID among hospitalised migrant and non-migrant patients in the Netherlands: a retrospective …
FP Chilunga, B Appelman, M van Vugt… - The Lancet Regional …, 2023 - thelancet.com
Background Comprehensive data on long COVID across ethnic and migrant groups are
lacking. We investigated incidence, nature of symptoms, clinical predictors, and duration of …
lacking. We investigated incidence, nature of symptoms, clinical predictors, and duration of …
Antiviral fibrils of self-assembled peptides with tunable compositions
The lasting threat of viral pandemics necessitates the development of tailorable first-
response antivirals with specific but adaptive architectures for treatment of novel viral …
response antivirals with specific but adaptive architectures for treatment of novel viral …
[HTML][HTML] Warmer ambient air temperatures reduce nasal turbinate and brain infection, but increase lung inflammation in the K18-hACE2 mouse model of COVID-19
Warmer climatic conditions have been associated with fewer COVID-19 cases. Herein we
infected K18-hACE2 mice housed at the standard animal house temperature of∼ 22° C, or …
infected K18-hACE2 mice housed at the standard animal house temperature of∼ 22° C, or …
A phosphodiesterase-4 inhibitor reduces lung inflammation and fibrosis in a hamster model of SARS-CoV-2 infection
Introduction The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)
infection involves pulmonary inflammation that can progress to acute respiratory distress …
infection involves pulmonary inflammation that can progress to acute respiratory distress …
A SARS-CoV-2 vaccine designed for manufacturability results in unexpected potency and non-waning humoral response
E Campbell, J Dobkin, LJ Osorio, A Kolloli… - Vaccines, 2023 - mdpi.com
The rapid development of several highly efficacious SARS-CoV-2 vaccines was an
unprecedented scientific achievement that saved millions of lives. However, now that SARS …
unprecedented scientific achievement that saved millions of lives. However, now that SARS …
[HTML][HTML] The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in infected and immune suppressed mice.
R Penrice-Randal, EG Bentley, P Sharma, A Kirby… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Objectives. Immunocompromised individuals are susceptible to severe COVID-19 and
potentially contribute to the emergence of variants with altered pathogenicity due to …
potentially contribute to the emergence of variants with altered pathogenicity due to …
Dynamics of temporal immune responses in nonhuman primates and humans immunized with COVID-19 vaccines
R Ravindran, H Kang, C McReynolds, GK Sanghar… - Plos one, 2023 - journals.plos.org
We assessed the humoral immune responses to a COVID-19 vaccine in a well-controlled
rhesus macaque model compared to humans immunized with two mRNA vaccines over …
rhesus macaque model compared to humans immunized with two mRNA vaccines over …
Modulations of Homeostatic ACE2, CD147, GRP78 Pathways Correlate with Vascular and Endothelial Performance Markers during Pulmonary SARS-CoV-2 Infection
The pathologic consequences of Coronavirus Disease-2019 (COVID-19) include elevated
inflammation and dysregulated vascular functions associated with thrombosis. In general …
inflammation and dysregulated vascular functions associated with thrombosis. In general …
Broad-Spectrum Heavily Mutated Monoclonal Antibody Isolated from COVID-19 Convalescent Vaccinee with Capacity to Neutralize SARS-CoV2 Variants Ranging …
Graphical Abstract In brief Choudhary et al. have isolated and characterized Acovimab, a
broadly neutralizing RBM-specific human monoclonal antibody with a relatively high level of …
broadly neutralizing RBM-specific human monoclonal antibody with a relatively high level of …