It is increasingly becoming clear that cancers are a symbiosis of diverse cell types and tumor
clones. Combined single-cell RNA sequencing, flow cytometry, and immunohistochemistry …

Appreciation of the properties of arsenic trioxide (ATO) has redefined the treatment
landscape for acute promyelocytic leukaemia (APL) and offers promise as a treatment for …

Abstract Background Treatment of Diffuse Large B Cell Lymphoma (DLBCL) patients with
rituximab and the CHOP treatment regimen is associated with frequent intrinsic and …

Epigenetic modifications have been found to play crucial roles in myelodysplastic neoplasm
(MDS) progression. Previously, we investigated genome-wide DNA methylation alterations …

Non-small cell lung cancer (NSCLC) is a common and aggressive primary malignancy
worldwide. Dysregulation of long non-coding RNAs (lncRNAs) has been shown to play an …

Aresenic trioxide (ATO) is proven to be active against leukaemia cells by inducing apoptosis
and differentiation. Even though ATO could effectively induce remissions of leukaemia cells …

Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML)
cytogenetically characterized by a balanced reciprocal translocation between chromosomes …

While it is increasingly becoming clear that cancers are a symbiosis of diverse cell types and
tumor clones, the tumor microenvironment (TME) in acute myeloid leukemias (AML) remains …

Current murine xenotransplantation models used as in vivo study models of human
leukemic processes, particularly in acute myeloid leukemia (AML) have failed to reconstruct …

While it is increasingly becoming clear that cancers are a symbiosis of diverse cell types
and tumor clones, the tumor supportive microenvironment (TSM) in acute myeloid …