Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples

J Williams, K Handique, K Wilson - US Patent 8,133,671, 2012 - Google Patents
The technology described herein generally relates to systems for extracting polynucleotides
from multiple samples, particularly from biological samples, and additionally to systems that …

Integrated system for processing microfluidic samples, and method of using the same

K Handique, SN Brahmasandra, K Ganesan… - US Patent …, 2015 - Google Patents
US9040288B2 - Integrated system for processing microfluidic samples, and method of
using the same - Google Patents US9040288B2 - Integrated system for processing …

Microfluidic cartridge and method of using same

K Handique - US Patent 8,709,787, 2014 - Google Patents
The present technology provides for a microfluidic substrate configured to carry out PCR on
a number of polynucleotide-containing samples in parallel. The substrate can be a single …

Automated pipetting apparatus having a combined liquid pump and pipette head system

J Williams, K Wilson - US Patent 8,287,820, 2012 - Google Patents
The technology described herein generally relates to systems for extracting polynucleotides
from multiple samples, par ticularly from biological samples, and additionally to systems that …

Methods and systems for fluid control in microfluidic devices

G Parunak - US Patent 6,575,188, 2003 - Google Patents
BACKGROUND Microfluidic systems include devices with features having dimensions on
the order of nanometers to 100s of um that cooperate to perform various desired functions. In …

Technology and applications of microengineered reactors

A Gavriilidis, P Angeli, E Cao, KK Yeong… - … research and design, 2002 - Elsevier
Microengineered reactors are a new type of reactor. Their novelty dictates a new approach
in design, which requires familiarization with the various manufacturing techniques and …

Microfluidic cartridge

K Handique - US Patent 8,105,783, 2012 - Google Patents
Related US Application Data (Continued)(63) Continuation-in-part of application No.
12/173,023, filed on Jul. 14, 2008, and a continuation-in-part of F () REIGN PATENT D …

Vapor escape microchannel heat exchanger

P Zhou, K Goodson, J Suntiago - US Patent 6,994,151, 2006 - Google Patents
A vapor escape membrane for use in a heat exchanging device, including a heat pipe or
heat sink that runs liquid into a cooling region positioned adjacent to the heat producing …

Method for processing polynucleotide-containing samples

B Wu, JS Althaus, N Phadke… - US Patent …, 2014 - Google Patents
Methods and systems for processing polynucleotides (eg, DNA) are disclosed. A processing
region includes one or more surfaces (eg, particle surfaces) modified with ligands that retain …

Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids

B Wu, K Ganesan, K Handique, G Parunak - US Patent 7,192,557, 2007 - Google Patents
The present invention relates to a microfluidic system for processing a cell-containing liquid.
The system includes a lysing zone to receive the cell-containing sample and a positioning …