The state of clinical trials of implantable brain–computer interfaces

KM Patrick-Krueger, I Burkhart… - Nature reviews …, 2025 - nature.com
Implanted brain–computer interfaces (iBCIs) translate brain activity recorded intracranially
into commands for virtual or physical machines to restore or rehabilitate motor, sensory or …

[HTML][HTML] Beyond language: The unspoken sensory-motor representation of the tongue in non-primates, non-human and human primates

D Bono, M Belyk, MR Longo, F Dick - Neuroscience & Biobehavioral …, 2022 - Elsevier
The English idiom “on the tip of my tongue” commonly acknowledges that something is
known, but it cannot be immediately brought to mind. This phrase accurately describes …

Brain control of bimanual movement enabled by recurrent neural networks

DR Deo, FR Willett, DT Avansino, LR Hochberg… - Scientific Reports, 2024 - nature.com
Brain-computer interfaces have so far focused largely on enabling the control of a single
effector, for example a single computer cursor or robotic arm. Restoring multi-effector motion …

[HTML][HTML] Shared control of bimanual robotic limbs with a brain-machine interface for self-feeding

DA Handelman, LE Osborn, TM Thomas… - Frontiers in …, 2022 - frontiersin.org
Advances in intelligent robotic systems and brain-machine interfaces (BMI) have helped
restore functionality and independence to individuals living with sensorimotor deficits; …

Decoding and geometry of ten finger movements in human posterior parietal cortex and motor cortex

C Guan, T Aflalo, K Kadlec, JG de Leon… - Journal of neural …, 2023 - iopscience.iop.org
Objective. Enable neural control of individual prosthetic fingers for participants with upper-
limb paralysis. Approach. Two tetraplegic participants were each implanted with a 96 …

Left hemisphere dominance for bilateral kinematic encoding in the human brain

CM Merrick, TC Dixon, A Breska, J Lin, EF Chang… - elife, 2022 - elifesciences.org
Neurophysiological studies in humans and nonhuman primates have revealed movement
representations in both the contralateral and ipsilateral hemispheres. Inspired by clinical …

Translating deep learning to neuroprosthetic control

DR Deo, FR Willett, DT Avansino, LR Hochberg… - bioRxiv, 2023 - biorxiv.org
Advances in deep learning have given rise to neural network models of the relationship
between movement and brain activity that appear to far outperform prior approaches. Brain …

Decoding multi-limb movements from two-photon calcium imaging of neuronal activity using deep learning

S Park, M Lipton, MC Dadarlat - Journal of neural engineering, 2024 - iopscience.iop.org
Objective. Brain–machine interfaces (BMIs) aim to restore sensorimotor function to
individuals suffering from neural injury and disease. A critical step in implementing a BMI is …

Effect of head-mounted virtual reality and vibrotactile feedback in ERD during motor imagery Brain–computer interface training

D Batista, G Caetano, M Fleury… - Brain-Computer …, 2024 - Taylor & Francis
Brain–computer interfaces (BCIs) can provide a non-muscular channel of control to stroke
patients for motor rehabilitation. This can be achieved through the use of motor imagery (MI) …

Maintained representations of the ipsilateral and contralateral limbs during bimanual control in primary motor cortex

KP Cross, EA Heming, DJ Cook… - Journal of …, 2020 - Soc Neuroscience
Primary motor cortex (M1) almost exclusively controls the contralateral side of the body.
However, M1 activity is also modulated during ipsilateral body movements. Previous work …