The pathophysiology of glaucoma is complex, multifactorial and not completely understood.
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …

The glaucomas are a group of conditions leading to irreversible sight loss and characterised
by progressive loss of retinal ganglion cells. Although not always elevated, intraocular …

Glaucoma is a group of diseases characterized by progressive optic nerve degeneration that
results in visual field loss and irreversible blindness. A crucial element in the …

Over 60 million people worldwide are diagnosed with glaucomatous optic neuropathy,
which is estimated to be responsible for 8.4 million cases of irreversible blindness globally …

There are many unanswered questions on the relation of intraocular pressure to glaucoma
development and progression. IOP itself cannot be distilled to a single, unifying value …

purpose. To determine whether acute experimental glaucoma in rats obstructs retrograde
transport of brain-derived neurotrophic factor (BDNF) to retinal ganglion cells (RGCs) …

Here, we use a mouse model (DBA/2J) to readdress the location of insult (s) to retinal
ganglion cells (RGCs) in glaucoma. We localize an early sign of axon damage to an …

This article is dedicated to Rosario Hernandez for her warm support of my own work and her
genuine enthusiasm for the work of her colleagues throughout her career. I first met Rosario …

Due to their permanent and close proximity to neurons, glial cells perform essential tasks for
the normal physiology of the retina. Astrocytes and Müller cells (retinal macroglia) provide …

OBJECTIVE: To confirm the advantages of the enhanced depth imaging (EDI) mode over the
standard mode of the Heidelberg Spectralis spectral domain optical coherence tomography …