A systematic review of clinical studies on variable proton Relative Biological Effectiveness (RBE)
Recently, a number of clinical studies have explored links between possible Relative
Biological Effectiveness (RBE) elevations and patient toxicities and/or image changes …
Biological Effectiveness (RBE) elevations and patient toxicities and/or image changes …
State-of-the-art and potential of experimental microdosimetry in ion-beam therapy
In radiotherapy, radiation-quality should be an expression of the biological and physical
characteristics of ionizing radiation such as spatial distribution of ionization or energy …
characteristics of ionizing radiation such as spatial distribution of ionization or energy …
Towards harmonizing clinical linear energy transfer (LET) reporting in proton radiotherapy: a European multi-centric study
Background Clinical data suggest that the relative biological effectiveness (RBE) in proton
therapy (PT) varies with linear energy transfer (LET). However, LET calculations are neither …
therapy (PT) varies with linear energy transfer (LET). However, LET calculations are neither …
Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients
J Eulitz, EGC Troost, L Klünder, F Raschke… - Radiotherapy and …, 2023 - Elsevier
Purpose Currently, there is an intense debate on variations in intra-cerebral radiosensitivity
and relative biological effectiveness (RBE) in proton therapy of primary brain tumours. Here …
and relative biological effectiveness (RBE) in proton therapy of primary brain tumours. Here …
[HTML][HTML] Outcomes of patients treated in the UK proton overseas programme: central nervous system group
Abstract Aims In 2008, the UK National Health Service started the Proton Overseas
Programme (POP), to provide access for proton beam therapy (PBT) abroad for selected …
Programme (POP), to provide access for proton beam therapy (PBT) abroad for selected …
Clinical benefit of range uncertainty reduction in proton treatment planning based on dual-energy CT for neuro-oncological patients
Objective: Several studies have shown that dual-energy CT (DECT) can lead to improved
accuracy for proton range estimation. This study investigated the clinical benefit of reduced …
accuracy for proton range estimation. This study investigated the clinical benefit of reduced …
Estimating the percentage of patients who might benefit from proton beam therapy instead of X-ray radiotherapy
Objectives: High-energy Proton Beam Therapy (PBT) commenced in England in 2018 and
NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We …
NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We …
An Overview of Cancer in Djibouti: Current Status, Therapeutic Approaches, and Promising Endeavors in Local Essential Oil Treatment
FM Abdoul-Latif, A Ainane, I Houmed Aboubaker… - Pharmaceuticals, 2023 - mdpi.com
Djibouti, a developing economy, grapples with significant socioeconomic obstacles and the
prevalence of infectious pathologies, including certain forms of neoplasms. These …
prevalence of infectious pathologies, including certain forms of neoplasms. These …
Impact of proton therapy on the DNA damage induction and repair in hematopoietic stem and progenitor cells
S Sioen, O Vanhove, B Vanderstraeten… - Scientific Reports, 2023 - nature.com
Proton therapy is of great interest to pediatric cancer patients because of its optimal depth
dose distribution. In view of healthy tissue damage and the increased risk of secondary …
dose distribution. In view of healthy tissue damage and the increased risk of secondary …
[HTML][HTML] Can the mean linear energy transfer of organs be directly related to patient toxicities for current head and neck cancer intensity-modulated proton therapy …
D Wagenaar, E Schuit, A van der Schaaf… - Radiotherapy and …, 2021 - Elsevier
Background and purpose The relative biological effectiveness (RBE) of proton therapy is
predicted to vary with the dose-weighted average linear energy transfer (LET d). However …
predicted to vary with the dose-weighted average linear energy transfer (LET d). However …