Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery

SC Cramer - Annals of neurology, 2008 - Wiley Online Library
Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …

Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance

DH Miller, F Barkhof, JA Frank, GJM Parker… - Brain, 2002 - academic.oup.com
MRI methods are widely used to follow the pathological evolution of multiple sclerosis in life
and its modification by treatment. To date, measures of the number and volume of …

Grey matter pathology in multiple sclerosis

JJG Geurts, F Barkhof - The Lancet Neurology, 2008 - thelancet.com
Multiple sclerosis (MS) has been classically regarded as a white matter disease. However,
recent histopathological studies have convincingly shown that grey matter regions are also …

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

SE Baranzini, J Wang, RA Gibson… - Human molecular …, 2009 - academic.oup.com
Multiple sclerosis (MS), a chronic disorder of the central nervous system and common cause
of neurological disability in young adults, is characterized by moderate but complex risk …

Functional magnetic resonance imaging

PM Matthews, P Jezzard - Journal of Neurology, Neurosurgery & …, 2004 - jnnp.bmj.com
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI)
is a powerful approach to defining activity in the healthy and diseased human brain. BOLD …

Functional magnetic resonance imaging correlates of fatigue in multiple sclerosis

M Filippi, MA Rocca, B Colombo, A Falini, M Codella… - Neuroimage, 2002 - Elsevier
Although fatigue is a common and troublesome symptom of multiple sclerosis (MS), its
pathogenesis is poorly understood. In this study, we used functional magnetic resonance …

The motor system shows adaptive changes in complex regional pain syndrome

C Maihöfner, R Baron, R DeCol, A Binder, F Birklein… - Brain, 2007 - academic.oup.com
The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that
may develop following injuries of the extremities. In the present study we sought to …

Applications of fMRI in translational medicine and clinical practice

PM Matthews, GD Honey, ET Bullmore - Nature Reviews Neuroscience, 2006 - nature.com
Functional MRI (fMRI) has had a major impact in cognitive neuroscience. fMRI now has a
small but growing role in clinical neuroimaging, with initial applications to neurosurgical …

Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis

N Evangelou, D Konz, MM Esiri, S Smith, J Palace… - Brain, 2001 - academic.oup.com
Axonal damage is found in both acute and chronic lesions of multiple sclerosis. Direct axon
counting in post-mortem tissue has suggested that smaller axons might have a greater …

Quantitative fMRI assessment of the differences in lateralization of language-related brain activation in patients with temporal lobe epilepsy

JE Adcock, RG Wise, JM Oxbury, SM Oxbury… - Neuroimage, 2003 - Elsevier
Defining language lateralization is important to minimize morbidity in patients treated
surgically for temporal lobe epilepsy (TLE). Functional magnetic resonance imaging (fMRI) …