[HTML][HTML] Global hospitalization trends for Crohn's disease and ulcerative colitis in the 21st century: a systematic review with temporal analyses

MJ Buie, J Quan, JW Windsor, S Coward… - Clinical …, 2023 - Elsevier
Background & Aims The evolving epidemiologic patterns of inflammatory bowel disease
(IBD) throughout the world, in conjunction with advances in therapeutic treatments, may …

translating STRIDE‐II into clinical reality–opportunities and challenges

A Dignass, S Rath, T Kleindienst… - Alimentary …, 2023 - Wiley Online Library
Background With the introduction of novel therapies for inflammatory bowel diseases
(IBD),'treat‐to‐target'strategies are increasingly discussed to improve short‐and long‐term …

[HTML][HTML] A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE) …

NM Noor, JC Lee, S Bond, F Dowling… - The Lancet …, 2024 - thelancet.com
Background Management strategies and clinical outcomes vary substantially in patients
newly diagnosed with Crohn's disease. We evaluated the use of a putative prognostic …

Treat‐to‐target and sequencing therapies in Crohn's disease

NM Garcia, NA Cohen, DT Rubin - United European …, 2022 - Wiley Online Library
Crohn's disease (CD) is a chronic immune‐mediated inflammatory condition which can
negatively impact a patient's quality of life. The traditional management strategy for CD has …

Crohn's disease

M Dolinger, J Torres, S Vermeire - The Lancet, 2024 - thelancet.com
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead
to progressive bowel damage and disability. The exact cause of Crohn's disease is …

CT-based radiomics signature of visceral adipose tissue for prediction of disease progression in patients with crohn's disease: a multicentre cohort study

X Li, N Zhang, C Hu, Y Lin, J Li, Z Li, E Cui, L Shi… - …, 2023 - thelancet.com
Background Visceral adipose tissue (VAT) is involved in the pathogenesis of Crohn's
disease (CD). However, data describing its effects on CD progression remain scarce. We …

Early biologic treatment decreases risk of surgery in Crohn's disease but not in ulcerative colitis: systematic review and meta-analysis

CCY Law, B Tkachuk, S Lieto, N Narula… - Inflammatory bowel …, 2023 - academic.oup.com
Abstract Background and Aims Inflammatory bowel disease (IBD) can lead to long-term
complications that significantly impact patients' quality of life and healthcare resource …

[HTML][HTML] Positioning biologics in the treatment of IBD: A practical guide–Which mechanism of action for whom?

P Juillerat, MM Grueber, R Ruetsch, G Santi… - Current research in …, 2022 - Elsevier
The number of available biological therapies have doubled over the last 10 years and the
arrival of novel molecules (interleukin 23p19 inhibitors) is ongoing alongside the …

Global, regional, and national burden of inflammatory bowel disease and its associated anemia, 1990 to 2019 and predictions to 2050: An analysis of the global …

S Wang, Z Dong, X Wan - Autoimmunity Reviews, 2023 - Elsevier
Aim Inflammatory bowel disease (IBD) exhibited a global increase in incidence over the past
decade. Understanding global burden of IBD can offer valuable insights for shaping future …

5‐aminosalicylate maintenance is not superior to no maintenance in patients with newly diagnosed Crohn's disease—A nationwide cohort study

O Atia, I Goren, TS Fischler… - Alimentary …, 2023 - Wiley Online Library
Summary Background 5‐aminosalicylates (5‐ASA) are widely used in Crohn's disease (CD)
despite guidelines advising otherwise. We aimed to assess in nationwide study the …