Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …

Ischemia‐reperfusion injury (IRI) has indeed been shown as a main complication of
hepatectomy, liver transplantation, trauma, and hypovolemic shock. A large number of …

Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …

Damage-associated molecular patterns are signalling molecules involved in inflammatory
responses and restoration of homeostasis. Chronic release of these molecules can also …

Hepatic ischemia reperfusion injury (HIRI) is a major hurdle in many clinical scenarios,
including liver resection and transplantation. Various studies and countless surgical events …

Exosomes are an emerging therapeutic tool for the treatment of tissue injuries. In the present
study, the protective effect of isolated exosomes from adipose‑derived stem cells (ADSCs …

Mitochondria are attractive targets for novel molecules to limit IRI-associated inflammation.
Although dynamic preservation techniques could serve as delivery tool for new therapeutic …

Thioacetamide (TAA), a classic liver toxic compound, is used to establish experimental
models of liver injury via induction of inflammation and oxidative stress. The current study …

Background Ischaemia-reperfusion (IR) injury makes a major contribution to graft damage
during kidney transplantation. Oxidative damage to mitochondria is an early event in IR …

Ischemia–reperfusion is a cascade of complex and interrelated pathological processes
underlying many human diseases, including such socially significant diseases as stroke …