According to the minimal criteria of the International Society of Cellular Therapy,
mesenchymal stem cells (MSCs) are a population of undifferentiated cells defined by their …

Mesenchymal stem cells have awakened a great deal of interest in regenerative medicine
due to their plasticity, and immunomodulatory and anti-inflammatory properties. They are …

Foxp3+ regulatory T cells (Treg cells) are essential for establishing and maintaining self-
tolerance, and also inhibit immune responses to innocuous environmental antigens …

Tendon disorders represent a very common pathology in today's population, and
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …

Periodontitis is a high prevalence oral disease which damages both the hard and soft tissue
of the periodontium, resulting in tooth mobility and even loss. Existing clinical treatment …

Tissue defects in the human body after trauma and injury require precise reconstruction to
regain function. Hence, there is a great demand for clinically translatable approaches with …

Mesenchymal stem cells (MSCs) are considered a potential tool for cell based regenerative
therapy due to their immunomodulatory property, differentiation potentials, trophic activity as …

Despite a major role of experimental animals in development of biomedical research, there
has been historical controversy surrounding animal research. Along with a strategy of 3Rs …

Adipose tissue presents a comparably easy source for obtaining stem cells, and more
studies are increasingly investigating the therapeutic potential of adipose-derived stem cells …

Vascularized composite allotransplants (VCAs) have unique properties because of diverse
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …