Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification

C Bergom, JA Bradley, AK Ng, P Samson, C Robinson… - Cardio Oncology, 2021 - jacc.org
Radiation therapy is an important component of cancer therapy for many malignancies. With
improvements in cardiac-sparing techniques, radiation-induced cardiac dysfunction has …

[HTML][HTML] Radiation-induced heart disease: a review of classification, mechanism and prevention

H Wang, J Wei, Q Zheng, L Meng, Y Xin… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an
important component of comprehensive treatment. RT improves survival in many cancers …

Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic …

H Strongman, S Gadd, A Matthews, KE Mansfield… - The Lancet, 2019 - thelancet.com
Background The past few decades have seen substantial improvements in cancer survival,
but concerns exist about long-term cardiovascular disease risk in survivors. Evidence is …

Practical recommendations for reporting F ine‐G ray model analyses for competing risk data

PC Austin, JP Fine - Statistics in medicine, 2017 - Wiley Online Library
In survival analysis, a competing risk is an event whose occurrence precludes the
occurrence of the primary event of interest. Outcomes in medical research are frequently …

Validation and modification of a prediction model for acute cardiac events in patients with breast cancer treated with radiotherapy based on three-dimensional dose …

VAB van den Bogaard, BDP Ta… - Journal of Clinical …, 2017 - ascopubs.org
Purpose A relationship between mean heart dose (MHD) and acute coronary event (ACE)
rate was reported in a study of patients with breast cancer (BC). The main objective of our …

Coronary artery disease in young women after radiation therapy for breast cancer: the WECARE Study

LE Carlson, GP Watt, ES Tonorezos, EJ Chow, AF Yu… - Cardio Oncology, 2021 - jacc.org
Background Radiation therapy (RT) for breast cancer increases risk of coronary artery
disease (CAD). Women treated for left-vs right-sided breast cancer receive greater heart …

[HTML][HTML] Radiation dose-response for risk of myocardial infarction in breast cancer survivors

JN Jacobse, FK Duane, NB Boekel… - International Journal of …, 2019 - Elsevier
Purpose Previous reports suggest that radiation therapy for breast cancer (BC) can cause
ischemic heart disease, with the radiation-related risk increasing linearly with mean whole …

Long-term heart-specific mortality among 347 476 breast cancer patients treated with radiotherapy or chemotherapy: a registry-based cohort study

J Weberpals, L Jansen, OJ Müller… - European heart …, 2018 - academic.oup.com
Aims Breast cancer survival has improved throughout the last decades, but treatment-
induced cardiotoxicity remains a major concern. This study aimed to investigate competing …

Risk factors of fluoropyrimidine induced cardiotoxicity among cancer patients: a systematic review and meta-analysis

C Li, S Ngorsuraches, C Chou, L Chen… - Critical Reviews in …, 2021 - Elsevier
Cancer patients experienced an increased risk of cardiotoxicity during fluoropyrimidine-
based chemotherapy (5-fluorouracil or capecitabine). We searched PubMed, PsycINFO, IPA …

Utility of deep inspiration breath hold for left-sided breast radiation therapy in preventing early cardiac perfusion defects: a prospective study

TM Zagar, O Kaidar-Person, X Tang, EE Jones… - International Journal of …, 2017 - Elsevier
Purpose To evaluate early cardiac single photon computed tomography (SPECT) findings
after left breast/chest wall postoperative radiation therapy (RT) in the setting of deep …