Depression and obesity are common conditions with major public health implications that
tend to co-occur within individuals. The relationship between these conditions is …

Resilience is the ability to cope with critical situations through the use of personal and
socially mediated resources. Since a lack of resilience increases the risk of developing …

Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Human brains vary across people and over time; such variation is not yet understood in
cellular terms. Here we describe a relationship between people's cortical neurons and …

Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for
neural development, and brain cells frequently contain somatic genomic variations that …

Anti-IgLON5 disease is a newly defined clinical entity characterized by a progressive course
with high disability and mortality rate. While precise pathogenetic mechanisms remain …

Background Autoimmunity might be associated with or implicated in sleep and
neurodegenerative disorders. We aimed to describe the features of a novel neurological …

Uncontrolled transforming growth factor-β (TGFβ) signaling promotes aggressive metastatic
properties in late-stage breast cancers. However, how TGFβ-mediated cues are directed to …

Neuronal activity influences genes involved in circuit development and information
processing. However, the molecular basis of this process remains poorly understood. We …