Obesity and metabolic disorders such as type 2 diabetes mellitus are accompanied by
increased lipid deposition in adipose and non-adipose tissues including liver, pancreas …

Commercially reared food animals encounter serial pathogenic and nonpathogenic immune
challenges throughout production. Because of the diversion of nutrients away from growth in …

Serum creatinine (SCr) has been widely used to estimate glomerular filtration rate (GFR).
Creatinine generation could be reduced in the setting of low skeletal muscle mass. Thus …

Muscle wasting is often associated with chronic inflammation. Because tumor necrosis factor
α (TNF‐α) has been implicated as a major mediator of cachexia, its effects on C2C12 …

Tumor necrosis factor α (TNFα) has been implicated as a mediator of muscle wasting
through nuclear factor kappa B (NF‐ΚB)‐dependent inhibition of myogenic differentiation …

The ex vivo effects of passive mechanical stretch on the activation of nuclear factor‐kappaB
(NF‐κB) pathways in skeletal muscles from normal and mdx mouse, a model of Duchenne …

TWEAK cytokine has been implicated in several biological responses including
inflammation, angiogenesis, and osteoclastogenesis. Here we have investigated the role of …

Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron
homeostasis. We have identified and sequenced a full-length cDNA for murine ferritin heavy …

The anthracycline antibiotic doxorubicin produces a characteristic myopathy in cardiac
muscle that limits its use in cancer therapy. We have shown in cultured neonatal rat cardiac …

Differentiation of muscle cells is characterized morphologically by the acquisition of
contractile filaments and characteristic shape changes, and on the molecular level by …