Heterocycles in breast cancer treatment: the use of pyrazole derivatives

S Ardevines, E Marqués-López… - Current Medicinal …, 2023 - ingentaconnect.com
Among the aromatic heterocycle rings, pyrazole–a five-membered ring with two adjacent
nitrogen atoms in its structure has been postulated as a potent candidate in the …

Transition Metal Complexes as Antimalarial Agents: A Review

A Mandal, R Kushwaha, AA Mandal, S Bajpai… - …, 2023 - Wiley Online Library
In antimalarial drug development research, overcoming drug resistance has been a major
challenge for researchers. Nowadays, several drugs like chloroquine, mefloquine …

Design, synthesis and biological evaluation of 1, 3-diphenyl-1H-pyrazole derivatives containing benzimidazole skeleton as potential anticancer and apoptosis …

TS Reddy, H Kulhari, VG Reddy, V Bansal… - European journal of …, 2015 - Elsevier
A series of forty different pyrazole containing benzimidazole hybrids (6–45) have been
designed, synthesized and evaluated for their potential anti-proliferative activity against …

Copper-Catalyzed Construction of Benzo[4,5]imidazo[2,1-a]isoquinolines Using Calcium Carbide as a Solid Alkyne Source

H Liu, Z Li - Organic Letters, 2021 - ACS Publications
A method for the synthesis of benzo [4, 5] imidazo [2, 1-a] isoquinolines through
Sonogashira cross-coupling/nucleophilic addition tandem reactions using calcium carbide …

Selective Synthesis of Benzimidazoles from o-Phenylenediamine and Aldehydes Promoted by Supported Gold Nanoparticles

MA Tzani, C Gabriel, IN Lykakis - Nanomaterials, 2020 - mdpi.com
We investigated the catalytic efficacy of supported gold nanoparticles (AuNPs) towards the
selective reaction between o-phenylenediamine and aldehydes that yields 2-substituted …

Theoretical design and preparation of ionic liquid-based magnetic nanoparticles for the magnetic dispersive solid-phase extraction of benzimidazoles in human …

R Chen, X Zhang, F Liu, C Liu, Q Peng… - Separation and Purification …, 2022 - Elsevier
Conductor-like screening model for realistic solvents (COSMO-RS) theoretical chemical
model is an effective tool for predicting the thermodynamic properties of solvents. In this …

Transition-metal-free synthesis of benzimidazoles mediated by KOH/DMSO

H Baars, A Beyer, SV Kohlhepp, C Bolm - Organic letters, 2014 - ACS Publications
Transition-Metal-Free Synthesis of Benzimidazoles Mediated by KOH/DMSO | Organic Letters
ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS Publications …

Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents

C Gao, B Li, B Zhang, Q Sun, L Li, X Li, C Chen… - bioorganic & medicinal …, 2015 - Elsevier
The discovery of new effective DNA-targeted antitumor agent is needed because of their
clinical significance. As acridines can intercalate into DNA and benzimidazoles have the …

VOSO4 catalyzed highly efficient synthesis of benzimidazoles, benzothiazoles, and quinoxalines

CS Digwal, U Yadav, AP Sakla, PVS Ramya… - Tetrahedron …, 2016 - Elsevier
Herein, we describe a highly efficient and eco-friendly protocol for the synthesis of
benzimidazoles, benzothiazoles, and quinoxalines using VOSO 4 as a catalyst in ethanol …

Design, synthesis and biological evaluation of novel indole-benzimidazole hybrids targeting estrogen receptor alpha (ER-α)

R Singla, KB Gupta, S Upadhyay, M Dhiman… - European journal of …, 2018 - Elsevier
In the course of efforts to develop novel selective estrogen receptor modulators (SERMs),
indole-benzimidazole hybrids were designed and synthesised by fusing the indole nucleus …