An update on new-age potential biomarkers for Parkinson's disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder that deals with
dopaminergic deficiency in Substantia nigra pars compact (SNpc) region of the brain …
dopaminergic deficiency in Substantia nigra pars compact (SNpc) region of the brain …
[HTML][HTML] Role of dietary and nutritional interventions in ceramide-associated diseases
Ceramides are important intermediates in sphingolipid metabolism and serve as signaling
molecules with independent biological significance. Elevated cellular and circulating …
molecules with independent biological significance. Elevated cellular and circulating …
NMR-based metabolomics identification of potential serum biomarkers of disease progression in patients with multiple sclerosis
Multiple sclerosis (MS) is a chronic and progressive neurological disorder, characterized by
neuroinflammation and demyelination within the central nervous system (CNS). The etiology …
neuroinflammation and demyelination within the central nervous system (CNS). The etiology …
Evolving Landscape of Parkinson's Disease Research: Challenges and Perspectives
Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
movement. It occurs due to a gradual deficit of dopamine-producing brain cells, particularly …
movement. It occurs due to a gradual deficit of dopamine-producing brain cells, particularly …
[HTML][HTML] Exploring environmental modifiers of LRRK2-associated Parkinson's disease penetrance: An exposomics and metagenomics pilot study on household dust
Pathogenic variants in the Leucine-rich repeat kinase 2 (LRRK2) gene are a primary
monogenic cause of Parkinson's disease (PD). However, the likelihood of developing PD …
monogenic cause of Parkinson's disease (PD). However, the likelihood of developing PD …
[HTML][HTML] Multiomics approach discloses lipids and metabolites profiles associated to Parkinson's disease stages and applied therapies
F Carrillo, NP Palomba, M Ghirimoldi, C Dido… - Neurobiology of …, 2024 - Elsevier
Profiling circulating lipids and metabolites in Parkinson's disease (PD) patients could be
useful not only to highlight new pathways affected in PD condition but also to identify …
useful not only to highlight new pathways affected in PD condition but also to identify …
Untargeted metabolomics profiling of gestational diabetes mellitus: insights into early diagnosis and metabolic pathway alterations
SM Aleidi, H Al Fahmawi, RH AlMalki… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction Gestational Diabetes Mellitus (GDM) is a metabolic disorder marked by Q10
hyperglycemia that can negatively affect both mothers and newborns. The increasing …
hyperglycemia that can negatively affect both mothers and newborns. The increasing …
Diagnosing Parkinson's disease and monitoring its progression: Biomarkers from combined GC-TOF MS and LC-MS/MS untargeted metabolomics
Parkinson's disease (PD) is a prevalent neurodegenerative disorder with a poorly
understood etiology. An accurate diagnosis of idiopathic PD remains challenging as …
understood etiology. An accurate diagnosis of idiopathic PD remains challenging as …
Lipids and α-Synuclein: adding further variables to the equation
J Schepers, T Löser, C Behl - Frontiers in Molecular Biosciences, 2024 - frontiersin.org
Aggregation of alpha-Synuclein (αSyn) has been connected to several neurodegenerative
diseases, such as Parkinson's disease (PD), dementia with Lewy Bodies (DLB), and multiple …
diseases, such as Parkinson's disease (PD), dementia with Lewy Bodies (DLB), and multiple …
Interaction between α-Synuclein and Bioactive Lipids: Neurodegeneration, Disease Biomarkers and Emerging Therapies
C Sanluca, P Spagnolo, R Mancinelli, MI De Bartolo… - Metabolites, 2024 - mdpi.com
The present review provides a comprehensive examination of the intricate dynamics
between α-synuclein, a protein crucially involved in the pathogenesis of several …
between α-synuclein, a protein crucially involved in the pathogenesis of several …