Impact of metabolic syndrome on neuroinflammation and the blood–brain barrier

P Van Dyken, B Lacoste - Frontiers in neuroscience, 2018 - frontiersin.org
Metabolic syndrome, which includes diabetes and obesity, is one of the most widespread
medical conditions. It induces systemic inflammation, causing far reaching effects on the …

Classification of diabetic retinopathy: Past, present and future

Z Yang, TE Tan, Y Shao, TY Wong, X Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetic retinopathy (DR) is a leading cause of visual impairment and blindness worldwide.
Since DR was first recognized as an important complication of diabetes, there have been …

Oxidative stress and microvascular alterations in diabetic retinopathy: future therapies

ML Rodríguez, S Pérez, S Mena-Mollá… - Oxidative Medicine …, 2019 - Wiley Online Library
Diabetes is a disease that can be treated with oral antidiabetic agents and/or insulin.
However, patients' metabolic control is inadequate in a high percentage of them and a major …

Anti-VEGF-resistant retinal diseases: a review of the latest treatment options

JO Wallsh, RP Gallemore - Cells, 2021 - mdpi.com
Anti-vascular endothelial growth factor (anti-VEGF) therapy currently plays a central role in
the treatment of numerous retinal diseases, most notably exudative age-related macular …

[PDF][PDF] Inflammatory and angiogenic biomarkers in diabetic retinopathy

S Kaštelan, I Orešković, F Bišćan, H Kaštelan… - Biochemia …, 2020 - hrcak.srce.hr
Review Page 1 Abstract Diabetic retinopathy (DR) is one of the most common microvascular
complications of diabetes mellitus (DM) and a leading cause of blindness in working-age …

Involvement of advanced glycation end products in the pathogenesis of diabetic retinopathy

J Xu, LJ Chen, J Yu, HJ Wang, F Zhang… - Cellular Physiology and …, 2018 - karger.com
Diabetic retinopathy (DR) is a common and devastating microvascular complication of
diabetes and a major cause of acquired blindness in young adults. Advanced glycation end …

A Novel Photosynthetic Biohybrid System for Microenvironment Regulation of Diabetes Retinopathy through Continuous Oxygen Supply and Nanozyme Cascade …

L Zhou, K Lan, X Huang, Y Huang, Y Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abstract According to International Diabetes Federation Diabetes Atlas statistics, diabetic
retinopathy (DR) is the leading cause of vision loss in blinding diseases. The underlying …

Endothelial cell dysfunction, coagulation, and angiogenesis in coronavirus disease 2019 (COVID-19)

AH Norooznezhad, K Mansouri - Microvascular research, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been led to a pandemic emergency. So far …

The impact of oxidative stress-induced mitochondrial dysfunction on diabetic microvascular complications

Z Zhang, Q Huang, D Zhao, F Lian, X Li… - Frontiers in …, 2023 - frontiersin.org
Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycaemia,
with absolute insulin deficiency or insulin resistance as the main cause, and causes damage …

MSC-derived exosomal lncRNA SNHG7 suppresses endothelial-mesenchymal transition and tube formation in diabetic retinopathy via miR-34a-5p/XBP1 axis

X Cao, LD Xue, Y Di, T Li, YJ Tian, Y Song - Life Sciences, 2021 - Elsevier
Aims Diabetic retinopathy (DR) is the most common complication of type 2 diabetes mellitus,
which could result in visual impairment. Accumulating studies have shown the implication of …