The central role of the gut microbiota in the pathophysiology and management of type 2 diabetes

DP Baars, MF Fondevila, AS Meijnikman… - Cell host & …, 2024 - cell.com
The inhabitants of our intestines, collectively called the gut microbiome, comprise fungi,
viruses, and bacterial strains. These microorganisms are involved in the fermentation of …

A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation

Z Ma, T Zuo, N Frey, AY Rangrez - Signal Transduction and Targeted …, 2024 - nature.com
The human microbiome is a complex and dynamic system that plays important roles in
human health and disease. However, there remain limitations and theoretical gaps in our …

The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

M Byndloss, S Devkota, F Duca, JH Niess… - Diabetes, 2024 - diabetesjournals.org
This article summarizes the state of the science on the role of the gut microbiota (GM) in
diabetes from a recent international expert forum organized by Diabetes, Diabetes Care …

Enzymatic production of xylooligosaccharide from lignocellulosic and marine biomass: A review of current progress, challenges, and its applications in food sectors

Y Lin, Y Dong, X Li, J Cai, L Cai, G Zhang - International Journal of …, 2024 - Elsevier
Over the last decade, xylooligosaccharides (XOS) have attracted great attentions because of
their unique chemical properties and excellent prebiotic effects. Among the current …

Gut microbial metabolic signatures in diabetes mellitus and potential preventive and therapeutic applications

E Garcia-Gutierrez, AK O'Mahony, RS Dos Santos… - Gut …, 2024 - Taylor & Francis
Diabetes mellitus can be subdivided into several categories based on origin and clinical
characteristics. The most common forms of diabetes are type 1 (T1D), type 2 diabetes (T2D) …

Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values

Y Wang, Y Li, L Bo, E Zhou, Y Chen… - Gut …, 2023 - Taylor & Francis
The musculoskeletal system is important for balancing metabolic activity and maintaining
health. Recent studies have shown that distortions in homeostasis of the intestinal …

Intestinal glucagon-like peptide-1: A new player associated with impaired counterregulatory responses to hypoglycaemia in type 1 diabetic mice

FX Jin, Y Wang, MN Li, RJ Li… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Impaired hypoglycaemic counterregulation has emerged as a critical
concern for diabetic patients who may be hesitant to medically lower their blood glucose …

Concise and Modular Chemoenzymatic Total Synthesis of Bisbenzylisoquinoline Alkaloids

J Wang, J Zhao, Z Yu, S Wang, F Guo… - Angewandte …, 2024 - Wiley Online Library
The bisbenzylisoquinoline alkaloids (bisBIAs) have attracted tremendous attention from the
synthetic community due to their diverse and intriguing biological activities. Herein, we …

Statins aggravate insulin resistance through reduced blood glucagon-like peptide-1 levels in a microbiota-dependent manner

J She, G Tuerhongjiang, M Guo, J Liu, X Hao, L Guo… - Cell Metabolism, 2024 - cell.com
Statins are currently the most common cholesterol-lowering drug, but the underlying
mechanism of statin-induced hyperglycemia is unclear. To investigate whether the gut …

Advancing lifelong precision medicine for cardiovascular diseases through gut microbiota modulation

B Shi, H Li, X He - Gut Microbes, 2024 - Taylor & Francis
The gut microbiome is known as the tenth system of the human body that plays a vital role in
the intersection between health and disease. The considerable inter-individual variability in …