[HTML][HTML] Advances in Flavonoid Research: Sources, Biological Activities, and Developmental Prospectives

B Hao, Z Yang, H Liu, Y Liu, S Wang - Current Issues in Molecular …, 2024 - mdpi.com
At present, the occurrence of a large number of infectious and non-communicable diseases
poses a serious threat to human health as well as to drug development for the treatment of …

[HTML][HTML] Generation and Accumulation of Various Advanced Glycation End-Products in Cardiomyocytes May Induce Cardiovascular Disease

T Takata, S Inoue, T Masauji, K Miyazawa… - International Journal of …, 2024 - ncbi.nlm.nih.gov
Cardiomyocyte dysfunction and cardiovascular diseases (CVDs) can be classified as
ischemic or non-ischemic. We consider the induction of cardiac tissue dysfunction by …

[HTML][HTML] Novel In Vitro Assay of the Effects of Kampo Medicines against Intra/Extracellular Advanced Glycation End-Products in Oral, Esophageal, and Gastric …

T Takata, Y Motoo - Metabolites, 2023 - mdpi.com
Kampo medicines are Japanese traditional medicines developed from Chinese traditional
medicines. The action mechanisms of the numerous known compounds have been studied …

[HTML][HTML] Influence of Thermal Treatment on the Composition of Alpinia officinarum Rhizome

J Zagórska, K Pietrzak, W Kukula-Koch… - International Journal of …, 2024 - mdpi.com
Alpinia officinarum is a representative of the Zingiberaceae family, which is known for its
wide use in the food and pharmaceutical industries also due to its precious pharmacological …

Potential Role of Bmal1 in Lipopolysaccharide-Induced Depression-Like Behavior and its Associated" Inflammatory Storm"

DD Xu, ZQ Hou, YY Xu, J Liang, YJ Gao… - Journal of Neuroimmune …, 2024 - Springer
Inflammation plays an important role in the pathogenesis of depression; however, the
underlying mechanisms remain unclear. Apart from the disordered circadian rhythm in …

Targeting TRPV1 signaling: Galangin improves ethanol-induced gastric mucosal injury

K Lin, Z Wang, E Wang, X Zhang, X Liu, F Feng… - Journal of …, 2024 - Elsevier
Ethnopharmacological Relevance Galangin, a bioactive compound extracted from Alpinia
officinarum Hance (Zingiberaceae), a plant with significant ethnopharmacological …

Discovery of first-in-class highly selective TRPV1 antagonists with dual analgesic and hypoglycemic effects

C Liu, W Wang, S Zhao, S Chen, H Chen… - Bioorganic & Medicinal …, 2024 - Elsevier
Analgesia and blood sugar control are considered as two main unmet clinical needs for
diabetes related neuropathic pain patients. Transient receptor potential vanilloid type-1 …

Estimating flavonoid oxidation potentials: mechanisms and charge-related regression models

A Miličević - Arhiv za higijenu rada i toksikologiju, 2023 - hrcak.srce.hr
Sažetak In this paper, I tested our quadratic regression models for the estimation of flavonoid
oxidation potentials based on spin populations, the differences in the net atomic charges …

Gastroprotective effect of vanillic acid against ethanol-induced gastric injury in rats: involvement of the NF-κB signalling and anti-apoptosis role

S Arabacı Tamer, GG Eskiler, F Ercan - Molecular Biology Reports, 2024 - Springer
Abstract Background Vanillic acid (VA; 4-hydroxy-3-methoxybenzoic acid) is a flavouring
agent found in various natural sources such as olives, fruits, and green tea. While VA …

[HTML][HTML] Analgesic and anti-inflammatory effects of galangin: a potential pathway to inhibit transient receptor potential vanilloid 1 receptor activation

K Lin, D Fu, Z Wang, X Zhang, C Zhu - The Korean Journal of Pain, 2024 - ncbi.nlm.nih.gov
Background Galangin, commonly employed in traditional Chinese medicine for its diverse
medicinal properties, exhibits potential in treating inflammatory pain. Nevertheless, its …