Data mining technology can search for potentially valuable knowledge from a large amount
of data, mainly divided into data preparation and data mining, and expression and analysis …

Osteoarthritis (OA) is one of the most commonly occurring forms of arthritis in the world
today. It is a debilitating chronic illness causing pain and immense discomfort to the affected …

Inflammation is a variable feature of osteoarthritis (OA), associated with joint symptoms and
progression of disease. Signs of inflammation can be observed in joint fluids and tissues …

Post-traumatic arthritis (PTA) develops after an acute direct trauma to the joints. PTA causes
about 12% of all osteoarthritis cases, and a history of physical trauma may also be found in …

Evidence has been building that the pathologic drive for development of osteoarthritis (OA)
involves more than simple mechanical “wear and tear.” Inflammatory mechanisms play an …

In genetic regulatory networks (GRNs), gene mutations often occur in a stochastic manner.
As an important model of GRNs, gene mutations of Boolean networks are always described …

MicroRNAs have been shown to function in cartilage development and homeostasis, as well
as in progression of osteoarthritis. The objective of the current study was to identify …

Osteoarthritis causes debilitating pain and disability, resulting in a considerable
socioeconomic burden, yet no drugs are available that prevent disease onset or …

Objective Identify gene changes in articular cartilage of the medial tibial plateau (MTP) at 2,
4 and 8 weeks after destabilisation of the medial meniscus (DMM) in mice. Compare our …

We investigated the role of periostin, an extracellular matrix protein, in the pathophysiology
of osteoarthritis (OA). In OA, dysregulated gene expression and phenotypic changes in …