[HTML][HTML] Emerging landscape in psoriasis management: from topical application to targeting biomolecules
Psoriasis is a chronic autoimmune skin disorder affecting 2–3% of the world population. It
has characteristic features such as increased keratinocyte proliferation and production of …
has characteristic features such as increased keratinocyte proliferation and production of …
Sulfoximines as rising stars in modern drug discovery? Current status and perspective on an emerging functional group in medicinal chemistry
Sulfoximines have been largely disregarded in medicinal chemistry for a long time.
However, recently, they have risen to the apparent level of stardom on the drug discovery …
However, recently, they have risen to the apparent level of stardom on the drug discovery …
An insight into biomolecules for the treatment of skin infectious diseases
HP Felgueiras - Pharmaceutics, 2021 - mdpi.com
In assigning priorities, skin infectious diseases are frequently classified as minor when
compared to infectious diseases of high mortality rates, such as tuberculosis or HIV …
compared to infectious diseases of high mortality rates, such as tuberculosis or HIV …
[HTML][HTML] Systemic psoriasis therapies and comorbid disease in patients with psoriasis: a review of potential risks and benefits
D Mikhaylov, PW Hashim, T Nektalova… - The Journal of clinical …, 2019 - ncbi.nlm.nih.gov
Psoriasis is an inflammatory skin disease that is associated with many comorbidities.
Several psoriasis treatments approved by the United States Food and Drug Administration …
Several psoriasis treatments approved by the United States Food and Drug Administration …
Nanodermatology‐based solutions for psoriasis: state‐of‐the art and future prospects
G Damiani, A Pacifico, DM Linder… - Dermatologic …, 2019 - Wiley Online Library
Nanodermatology is an emerging, multidisciplinary science, arising from the convergence of
nanotechnology, pharmacology, physics/biophysics, chemistry/biochemistry, chemical …
nanotechnology, pharmacology, physics/biophysics, chemistry/biochemistry, chemical …
A Scalable Approach to Assess the Safety of Recently Marketed Systemic Treatments for Atopic Dermatitis in Clinical Practice: First Analysis Cycle of a Sequential …
Targeted systemic immune-modulating drugs to treat atopic dermatitis were highly
efficacious in randomized trials. Trials with limited number of subjects leave questions about …
efficacious in randomized trials. Trials with limited number of subjects leave questions about …
[HTML][HTML] Immunogenicity of guselkumab is not clinically relevant in patients with moderate-to-severe plaque psoriasis
Y Zhu, JC Marini, M Song, B Randazzo… - Journal of Investigative …, 2019 - Elsevier
In two pivotal phase 3 studies (VOYAGE-1 [ClinicalTrials. gov ID NCT02207231] and
VOYAGE-2 [ClinicalTrials. gov ID NCT02207244]), patients (n= 1,829) with moderate-to …
VOYAGE-2 [ClinicalTrials. gov ID NCT02207244]), patients (n= 1,829) with moderate-to …
Tildrakizumab: a review in moderate-to-severe plaque psoriasis
JE Frampton - American Journal of Clinical Dermatology, 2019 - Springer
Tildrakizumab (tildrakizumab-asmn in the USA)[Ilumetri®; Ilumya™] is a humanized
monoclonal antibody (mAb) that selectively targets the p19 subunit of interleukin (IL)-23 …
monoclonal antibody (mAb) that selectively targets the p19 subunit of interleukin (IL)-23 …
Biologics for psoriasis: What is new?
Etiology of psoriasis is unclear but environmental, genetic, and immune factors act
significant roles in the pathogenesis of this disease. Helper T cells (TH), plasmoid, and …
significant roles in the pathogenesis of this disease. Helper T cells (TH), plasmoid, and …
A review of the efficacy and safety for biologic agents targeting IL-23 in treating psoriasis with the focus on tildrakizumab
FM Ghazawi, F Mahmood, L Kircik, Y Poulin… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a chronic and debilitating inflammatory immune-mediated skin disorder. Several
cytokines including interleukin (IL)-23 were demonstrated to play a central role in the …
cytokines including interleukin (IL)-23 were demonstrated to play a central role in the …