Nonhomologous end joining (NHEJ) refers to a set of genome maintenance pathways in
which two DNA double-strand break (DSB) ends are (re) joined by apposition, processing …

Although the full aetiology of autism spectrum disorder (ASD) is unknown, familial and twin
studies demonstrate high heritability of 60–90%, indicating a predominant role of genetics in …

Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB)
repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A …

To cope with DNA double strand break (DSB) genotoxicity, cells have evolved two main
repair pathways: homologous recombination which uses homologous DNA sequences as …

Genomic structural variation, which can be defined as differences in the copy number,
orientation, or location of relatively large DNA segments, is not only crucial in evolution, but …

Mitochondrial DNA (mtDNA) deletions are associated with various mitochondrial disorders.
The deletions identified in humans are flanked by short, directly repeated mitochondrial DNA …

DNA repair, one of the fundamental processes occurring in a cell, safeguards the genome
and maintains its integrity. Among various DNA lesions, double‐strand breaks are …

DNA strand breaks arise continuously in cells and can lead to chromosome rearrangements
and genome instability or cell death. The commonest DNA breaks are DNA single-strand …

Mitochondrial DNA is frequently exposed to oxidative damage, as compared to nuclear
DNA. Previously, we have shown that while microhomology-mediated end joining can …

Background The consumption of berry fruits, including strawberries, has been suggested to
have beneficial effects against oxidative stress mediated diseases. Berries contain multiple …