Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

C Tapeinos, M Battaglini, G Ciofani - Journal of Controlled Release, 2017 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment

P Maceira-Elvira, T Popa, AC Schmid… - … of neuroengineering and …, 2019 - Springer
Stroke is one of the main causes of long-term disability worldwide, placing a large burden on
individuals and society. Rehabilitation after stroke consists of an iterative process involving …

Healthy lifestyle and life expectancy with and without Alzheimer's dementia: population based cohort study

K Dhana, OH Franco, EM Ritz, CN Ford, P Desai… - bmj, 2022 - bmj.com
Objective To determine the impact of lifestyle factors on life expectancy lived with and
without Alzheimer's dementia. Design Prospective cohort study. Setting The Chicago Health …

Post‐stroke cognitive impairment is common even after successful clinical recovery

H Jokinen, S Melkas, R Ylikoski… - European journal of …, 2015 - Wiley Online Library
Background and purpose Cognitive impairment is common after stroke, but the prevalence
and long‐term significance of the diverse neuropsychological deficits on functional outcome …

Clinical outcomes of transplanted modified bone marrow–derived mesenchymal stem cells in stroke: a phase 1/2a study

GK Steinberg, D Kondziolka, LR Wechsler… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Preclinical data suggest that cell-based therapies have the
potential to improve stroke outcomes. Methods—Eighteen patients with stable, chronic …

Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial

F Chollet, J Tardy, JF Albucher, C Thalamas… - The Lancet …, 2011 - thelancet.com
Background Hemiplegia and hemiparesis are the most common deficits caused by stroke. A
few small clinical trials suggest that fluoxetine enhances motor recovery but its clinical …

Measurements of acute cerebral infarction: a clinical examination scale.

T Brott, HP Adams Jr, CP Olinger, JR Marler… - Stroke, 1989 - Am Heart Assoc
We designed a 15-item neurologic examination stroke scale for use in acute stroke therapy
trials. In a study of 24 stroke patients, interrater reliability for the scale was found to be high …

Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial

W Stummer, U Pichlmeier, T Meinel, OD Wiestler… - The lancet …, 2006 - thelancet.com
Background 5-aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular
accumulation of fluorescent porphyrins in malignant gliomas—a finding that is under …

[HTML][HTML] Mild cognitive impairment and dementia prevalence: the Atherosclerosis Risk in Communities Neurocognitive Study

DS Knopman, RF Gottesman, AR Sharrett… - Alzheimer's & Dementia …, 2016 - Elsevier
Introduction We examined prevalence of mild cognitive impairment (MCI) and dementia in
the Atherosclerosis Risk in Communities (ARIC) Neurocognitive study. Methods Beginning …