Is graphene shortening the path toward spinal cord regeneration?

AF Girão, MC Serrano, A Completo, PAAP Marques - ACS nano, 2022 - ACS Publications
Along with the development of the next generation of biomedical platforms, the inclusion of
graphene-based materials (GBMs) into therapeutics for spinal cord injury (SCI) has potential …

Spinal cord gray matter segmentation using deep dilated convolutions

CS Perone, E Calabrese, J Cohen-Adad - Scientific reports, 2018 - nature.com
Gray matter (GM) tissue changes have been associated with a wide range of neurological
disorders and were recently found relevant as a biomarker for disability in amyotrophic …

[HTML][HTML] Quantitative MRI of rostral spinal cord and brain regions is predictive of functional recovery in acute spinal cord injury

M Seif, A Curt, AJ Thompson, P Grabher, N Weiskopf… - NeuroImage: Clinical, 2018 - Elsevier
Objective To reveal the immediate extent of trauma-induced neurodegenerative changes
rostral to the level of lesion and determine the predictive clinical value of quantitative MRI …

High-spatial-resolution three-dimensional imaging of human spinal cord and column anatomy with postmortem X-ray phase-contrast micro-CT

GE Barbone, A Bravin, A Mittone, S Grosu, J Ricke… - Radiology, 2021 - pubs.rsna.org
Background Modern high-spatial-resolution radiologic methods enable increasingly detailed
volumetric postmortem investigations of human neuroanatomy for diagnostic, research, and …

[HTML][HTML] Overcoming challenges of the human spinal cord tractography for routine clinical use: a review

C Dauleac, C Frindel, P Mertens, T Jacquesson… - Neuroradiology, 2020 - Springer
The spinal cord (SC) is a dense network of billions of fibers in a small volume surrounded by
bones that makes tractography difficult to perform. We aim to provide a review collecting all …

Preferential activation of proprioceptive and cutaneous sensory fibers compared to motor fibers during cervical transcutaneous spinal cord stimulation: a …

RM de Freitas, M Capogrosso, T Nomura… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. Cervical transcutaneous spinal cord stimulation (tSCS) is a promising technology
that can support motor function recovery of upper-limbs after spinal cord injury. Its efficacy …

Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency

MS Nagree, J Rybova, A Kleynerman… - Communications …, 2023 - nature.com
Mutations in ASAH1 have been linked to two allegedly distinct disorders: Farber disease
(FD) and spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME). We …

[PDF][PDF] Spinal motor mapping by epidural stimulation of lumbosacral posterior roots in humans

US Hofstoetter, I Perret, A Bayart, P Lackner, H Binder… - Iscience, 2021 - cell.com
Epidural electrical stimulation of the spinal cord is an emergent strategy for the neurological
recovery of lower-extremity motor function. Motoneuron pools are thought to be recruited by …

HARDI-ZOOMit protocol improves specificity to microstructural changes in presymptomatic myelopathy

R Labounek, J Valošek, T Horák, A Svátková… - Scientific reports, 2020 - nature.com
Diffusion magnetic resonance imaging (dMRI) proved promising in patients with non-
myelopathic degenerative cervical cord compression (NMDCCC), ie, without clinically …

[HTML][HTML] Scattered Light Imaging: Resolving the substructure of nerve fiber crossings in whole brain sections with micrometer resolution

M Menzel, JA Reuter, D Gräßel, M Huwer, P Schlömer… - NeuroImage, 2021 - Elsevier
For developing a detailed network model of the brain based on image reconstructions, it is
necessary to spatially resolve crossing nerve fibers. The accuracy hereby depends on many …