Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Corneal epithelial defects and excessive wound healing might lead to severe complications.
As stem cells can self-renew infinitely, they are a promising solution for regenerating the …

The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …

There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

Ocular complications from diabetes mellitus are common. Diabetic keratopathy, the most
frequent clinical condition affecting the human cornea, is a potentially sight-threatening …

Abstract Purpose Extracellular vesicles (EVs) derived from mesenchymal stromal cells
(MSCs) have been demonstrated to possess great potential in preclinical models. An …

Wound healing is a complex biological process that is impaired under diabetes conditions.
Chronic non-healing wounds in diabetes are some of the most expensive healthcare …

Diabetes mellitus (DM) is a chronic systemic disease with increasing prevalence globally.
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …

Chronic metabolic diseases such as diabetes are characterized by delayed wound healing
and a dysregulation of the inflammatory phase of wound repair. Our study focuses on …

Exosomes, nanosized extracellular vesicles of 30–150 nm, are shed by almost all cell types.
Bearing proteins, lipids, RNAs, and DNAs, exosomes have emerged as vital biological …