Heterocyclic compounds account for the most prominent and diverse class of organic
compounds. A significant number of heterocyclic compounds have been synthesized up to …

Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …

One of the interesting research fields is developing and assessing novel metal-containing
medications. A new isatin-3-thiosemicarbazone derivative 4 was synthesized by two …

To overcome numerous health disorders, heterocyclic structures of synthetic or natural origin
are utilized, and notably, the emergence of various side effects of existing drugs used for …

The prevalence of diabetes mellitus is on the rise, which demands the identification of novel
antidiabetic drugs. There is a need for safer and more effective alternatives because the …

Herein, an efficient synthesis of spiro-indoline-pyrano [3, 2-c] quinolines derivatives of
spiroxindolines by the water-mediated three-component condensation reaction of 2 …

An efficient diastereoselective route is developed to get access to novel spiropyrrolo [1, 2-a]
isoquinoline-oxindole skeletons by a one-pot three-component [3+ 2] cycloaddition reaction …

Azomethine ylides are nitrogen-based three-atom components commonly used in [3+ 2]-
cycloaddition reactions with various unsaturated 2π-electron components. These reactions …

A highly stereoselective, three-component method has been developed to synthesize
pyrrolidine and pyrrolizidine containing spirooxindole derivatives. The interaction between …

Rhodanine has been recognized as a privileged scaffold in medicinal chemistry due to its
well-known ability to demonstrate a broad range of biological activities. The possibility of …