MALDI Imaging mass spectrometry has entered the field of tissue-based research by
providing unique advantages for analyzing tissue specimen in an unprecedented detail. A …

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is
emerging as a powerful tool for investigating the distribution of molecules within biological …

Accurate quantitative analysis of endogenous analytes is essential for several clinical and
non-clinical applications. LC–MS/MS is the technique of choice for quantitative analyses …

Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for
the localization of molecules in biological tissues. In drug discovery and development …

Imaging mass spectrometry (IMS) using matrix-assisted laser desorption ionization (MALDI)
is a new and effective tool for molecular studies of complex biological samples such as …

The full potential of imaging mass spectrometry (IMS) as a tool in drug development will not
be realized until reliable quantitative information can be integrated with the molecular …

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful tool for investigating the distribution of proteins and small molecules within …

Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …

A new approach is described for imaging mass spectrometry analysis of drugs and
metabolites in tissue using matrix-assisted laser desorption ionization-Fourier transform ion …

Significant advances in mass spectrometry imaging (MSI) have pushed the boundaries in
obtaining spatial information and quantification in biological samples. Quantitative MSI …