Extracellular signal-regulated kinase (ERK) has been recognized as a critical regulator in
various physiological and pathological processes. Extensive research has elucidated the …

Embryonic development hinges on effective coordination of molecular events across space
and time. Waves have recently emerged as constituting an ubiquitous mechanism that …

Injury induces systemic responses, but their functions remain elusive. Mechanisms that can
rapidly synchronize wound responses through long distances are also mostly unknown …

Targeted and specific induction of cell death in an individual or groups of cells hold the
potential for new insights into the response of tissues or organisms to different forms of …

In response to different cellular stresses, the transcription factor p53 undergoes different
dynamics. p53 dynamics, in turn, control cell fate. However, distinct stresses can generate …

What regulates the spatiotemporal distribution of cell elimination in tissues remains largely
unknown. This is particularly relevant for epithelia with high rates of cell elimination where …

Damaged or superfluous cells are typically eliminated by apoptosis. Although apoptosis is a
cell-autonomous process, apoptotic cells communicate with their environment in different …

Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …

Signaling by the extracellular signal-regulated kinase (ERK) pathway controls many cellular
processes, including cell division, death, and differentiation. In this second installment of a …

Regulated cell death (RCD) controls the removal of dispensable, infected or malignant cells,
and is thus essential for development, homeostasis and immunity of multicellular organisms …