Neuronal Kv7 channels underlie a voltage-gated non-inactivating potassium current known
as the M-current. Due to its particular characteristics, Kv7 channels show pronounced …

Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

The purpose of this review is to bridge the gap between earlier literature on striatal
cholinergic interneurons and mechanisms of microcircuit interaction demonstrated with the …

The degeneration of mesencephalic dopaminergic neurons that innervate the basal ganglia
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …

The dorsolateral striatum (DLS) receives excitatory inputs from both sensory and motor
cortical regions. In the neocortex, sensory responses are affected by motor activity, however …

Parkinson's disease (PD) is a movement disorder caused by the loss of dopaminergic
innervation, particularly to the striatum. PD patients often exhibit sensory impairments, yet …

Giant, aspiny cholinergic interneurons (ChIs) have long been known to be key nodes in the
striatal circuitry controlling goal‐directed actions and habits. In recent years, new …

A dynamic equilibrium between dopamine and acetylcholine (ACh) is essential for striatal
circuitry and motor function, as imbalances are associated with Parkinson's disease (PD) …

Centrally released corticotropin-releasing factor or hormone (extrahypothalamic CRF or
CRH) in the brain is involved in the behavioral and emotional responses to stress. The …

For roughly the last 30 years, the notion that striatal dopamine (DA) depletion was the critical
determinant of network pathophysiology underlying the motor symptoms of Parkinson's …