This review is focused on the challenges in standardising and optimising molecular testing
workflow in cytopathology. Although cytological samples yield optimal quality DNA, whose …

Context.—The need for appropriate specimen use for ancillary testing has become more
commonplace in the practice of pathology. This, coupled with improvements in technology …

Minimally invasive procedures such as endobronchial ultrasound‐guided transbronchial
needle aspiration (EBUS‐TBNA) must yield not only good quality and quantity of material for …

Detection of extremely rare variant alleles within a complex mixture of DNA molecules is
becoming increasingly relevant in many areas of clinical and basic research, such as the …

BACKGROUND In recent years, there have been increasing indications for percutaneous
renal biopsy. Fine‐needle aspiration (FNA), with or without core needle biopsy (CB), has …

BACKGROUND The ability to produce adequate cell blocks profoundly impacts the
diagnostic usefulness of cytology specimens. Cell blocks are routinely processed from fine …

Until a few years ago, only lung cancer histological specimens were considered suitable for
testing epidermal growth factor receptor (EGFR) mutations. Then, several retrospective …

Optical imaging modalities are emerging as digital microscopy tools for tissue examination.
The investigation of these techniques for potential applications in anatomic pathology …

Objective: The aim of this study was to investigate epidermal growth factor receptor (EGFR)
gene mutations and anaplastic lymphoma kinase (ALK) gene rearrangements using …

In the past 5 years, there has arguably been a shift in the pathologic diagnosis of lung
cancer, especially adenocarcinoma, moving toward a more patient-centered approach to …