Spatial omics technologies at multimodal and single cell/subcellular level
Spatial omics technologies enable a deeper understanding of cellular organizations and
interactions within a tissue of interest. These assays can identify specific compartments or …
interactions within a tissue of interest. These assays can identify specific compartments or …
Conditioning of the immune system by the microbiome
DB Graham, RJ Xavier - Trends in Immunology, 2023 - cell.com
The human intestinal microbiome has coevolved with its host to establish a stable
homeostatic relationship with hallmark features of mutualistic symbioses, yet the mechanistic …
homeostatic relationship with hallmark features of mutualistic symbioses, yet the mechanistic …
LIANA+ provides an all-in-one framework for cell–cell communication inference
The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …
development of many approaches to infer cell–cell communication, each capturing only a …
Community standards and future opportunities for synthetic communities in plant–microbiota research
Harnessing beneficial microorganisms is seen as a promising approach to enhance
sustainable agriculture production. Synthetic communities (SynComs) are increasingly …
sustainable agriculture production. Synthetic communities (SynComs) are increasingly …
Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes
The exchange of mobile genetic elements (MGEs) facilitates the spread of functional traits
including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs …
including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs …
Enablers and challenges of spatial omics, a melting pot of technologies
T Alexandrov, J Saez‐Rodriguez… - Molecular Systems …, 2023 - embopress.org
Spatial omics has emerged as a rapidly growing and fruitful field with hundreds of
publications presenting novel methods for obtaining spatially resolved information for any …
publications presenting novel methods for obtaining spatially resolved information for any …
Integrating single-cell multi-omics and prior biological knowledge for a functional characterization of the immune system
The immune system comprises diverse specialized cell types that cooperate to defend the
host against a wide range of pathogenic threats. Recent advancements in single-cell and …
host against a wide range of pathogenic threats. Recent advancements in single-cell and …
Navigating beyond associations: opportunities to establish causal relationships between the gut microbiome and colorectal carcinogenesis
The gut microbiota has been recognized as an important determinant in the initiation and
progression of colorectal cancer (CRC), with recent studies shining light on the molecular …
progression of colorectal cancer (CRC), with recent studies shining light on the molecular …
LIANA+: an all-in-one cell-cell communication framework
The growing availability of single-cell and spatially-resolved transcriptomics has led to the
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …
Next-Generation Sequencing-Based Spatial Transcriptomics: A Perspective from Barcoding Chemistry
Gene expression profiling of tissue cells with spatial context is in high demand to reveal cell
types, locations, and intercellular or molecular interactions for physiological and …
types, locations, and intercellular or molecular interactions for physiological and …