Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care: Second update 2022

S Kietaibl, A Ahmed, A Afshari… - European Journal of …, 2023 - journals.lww.com
Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

The safety and effectiveness of tranexamic acid in lumbar interbody fusion surgery: an updated meta-analysis of randomized controlled trials

GX Lin, CM Chen, MT Zhu, L Zheng - World Neurosurgery, 2022 - Elsevier
Objective Several previous meta-analyses have been published, followed by additional
randomized clinical trials investigating the effects of tranexamic acid (TXA) in patients …

Tranexamic acid use in the surgical arena: a narrative review

AM Mergoum, AS Mergoum, NJ Larson… - Journal of Surgical …, 2024 - Elsevier
Introduction Tranexamic acid (TXA) is a potent antifibrinolytic drug that inhibits the activation
of plasmin by plasminogen. While not a new medication, TXA has quickly gained traction …

Topical versus intravenous tranexamic acid in patients undergoing cardiac surgery: the DEPOSITION randomized controlled trial

A Lamy, DA Sirota, F Jacques, A Poostizadeh… - Circulation, 2024 - ahajournals.org
BACKGROUND: Although intravenous tranexamic acid is used in cardiac surgery to reduce
bleeding and transfusion, topical tranexamic acid results in lower plasma concentrations …

[HTML][HTML] Comparative efficacy and safety of different hemostatic medications during spinal surgery: a network meta-analysis

H Tan, S Pan, C Wei, Z Chen, T Chen - Medicine, 2023 - journals.lww.com
Background: Significant blood loss is still one of the most frequent issues in spinal surgery.
There were different hemostatic methods to prevent blood loss during spinal surgery …

[HTML][HTML] The Effects of Systemic Tranexamic Acid Administration on Drainage Volume, Length of Hospital Stay, and Postoperative Complications in Reduction …

S Magni, L Guggenheim, G Fournier, C Parodi… - Journal of Clinical …, 2024 - mdpi.com
Background: Reduction mammaplasty is a common, elective, and safe operation, usually
executed in healthy patients. Nonetheless, postoperative complications like bleeding and …

Efficacy and safety of tranexamic acid in patients undergoing thoracic surgery: a systematic review and PRIMSA-compliant meta-analysis

B Gao, Y Liu, Y Yao… - Journal of …, 2024 - Springer
Objectives Perioperative bleeding poses a significant issue during thoracic surgery.
Tranexamic acid (TXA) is one of the most commonly used antifibrinolytic agents for surgical …

氨甲环酸围术期应用进展

王文丽, 姚依婷, 杨春 - 中国临床药理学与治疗学, 2024 - manu41.magtech.com.cn
围术期出血与患者预后密切相关, 大量失血可导致严重不良事件的发生. 氨甲环酸是赖氨酸衍生
物, 通过竞争性阻断纤溶酶原上的赖氨酸结合位点发挥抗纤维蛋白溶解作用, 以达到止血功效 …

Effect of topical tranexamic acid on seroma formation in a rat mastectomy model

JH Lee, JY Ryu, JS Lee, KY Choi, HY Chung… - Aesthetic Plastic …, 2022 - Springer
Background Seroma is the most common complication after mastectomy and reconstruction
surgery. Therefore, this study aimed to determine whether the topical application of …

[HTML][HTML] Management of pericardial bleeding complications in percutaneous endo-epicardial catheter ablation for atrial fibrillation: A case for intrapericardial …

J Tonko, K Manoharan, R Amin… - HeartRhythm Case Reports, 2022 - Elsevier
Epicardial connections have been identified as an important cause for failed endocardial
atrial fibrillation (AF) ablations. Percutaneous and/or surgical techniques for stand-alone …