The promise of personalised medicine is now a clinical reality, with colorectal cancer
genetics at the forefront of this next major advance in clinical medicine. This is no more …

The promise of precision medicine is now a clinical reality. Advances in our understanding
of the molecular genetics of colorectal cancer (CRC) are leading to the development of a …

Lynch syndrome is the most common cause of hereditary colon cancer, and accounts for as
much as 3% of all colon and endometrial cancers. The identification and management of …

Purpose Molecular screening techniques are available to identify hereditary Lynch
syndrome in people with newly diagnosed colorectal cancer (CRC). We aimed to determine …

Lynch syndrome is the most common hereditary colorectal cancer syndrome and the most
common cause of hereditary endometrial cancer. Identifying and evaluating families for …

Qualitative comparative analysis (QCA) was developed over 25 years ago to bridge the
qualitative and quantitative research gap. On searching PubMed and the Journal of Mixed …

Objective Determine factors impacting the uptake of genetic counseling and results of
genetic testing following universal tumor testing for Lynch syndrome in patients with …

Lynch syndrome is the most common cause of inherited colorectal cancer, accounting for
approximately 3% of all colorectal cancer cases in the United States. In 2009, an evidence …

Purpose Universal tumor screening (UTS) for all colorectal cancer patients can improve the
identification of Lynch syndrome, the most common cause of hereditary colorectal cancer …

Background Mismatch repair proteins are ubiquitous keys in diverse cellular functions and
protects the genome by correcting mismatch as post replication error correction machinery …