[HTML][HTML] Shotgun proteomics of thyroid carcinoma exosomes–Insight into the role of exosomal proteins in carcinogenesis and thyroid homeostasis

M Surman, M Wilczak, U Jankowska… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Transport of molecules via exosomes is one of the factors involved in thyroid
cancer development, and transported molecules may serve as cancer biomarkers. The aim …

The effect of PEGylated graphene oxide nanoparticles on the Th17-Polarization of activated T helpers

S Zamorina, V Timganova, M Bochkova, K Shardina… - Materials, 2023 - mdpi.com
We investigated the direct effect of PEGylated graphene oxide (P-GO) nanoparticles on the
differentiation, viability, and cytokine profile of activated T helper type 17 (Th17) in vitro. The …

Hijacking Sexual Immuno-Privilege in GBM—An Immuno-Evasion Strategy

MA Sharpe, DS Baskin, AV Jenson… - International Journal of …, 2021 - mdpi.com
Regulatory T-cells (Tregs) are immunosuppressive T-cells, which arrest immune responses
to 'Self'tissues. Some immunosuppressive Tregs that recognize seminal epitopes suppress …

The pathogenic subpopulation of Th17 cells in obesity

N Todosenko, M Vulf, K Yurova… - Current …, 2021 - benthamdirect.com
Obesity is a metabolic disease characterized by a chronic subclinical inflammatory response
associated with an imbalance/dysregulation of cellular homeostasis in response to …

Identification of novel drug targets for liver cirrhosis and its potential side-effects by human plasma proteome

QA Xiao, WJ Zhao, J Yu, L Qin, XL Zhang, J Yu - Scientific Reports, 2024 - nature.com
Liver cirrhosis, a common liver disease, currently lacks specific targeted therapies. This
study investigates the potential therapeutic effects of serum circulating proteins on cirrhosis …

Genome− wide association analysis to search for new loci associated with stroke risk in Northwestern Chinese population

L Peng, Z Liu, P Liu, W Guo, T Liu, Z Lei, Q Chang… - Gene, 2024 - Elsevier
Abstract Background and Purpose Genetic factors play an important role in the
pathogenesis of stroke (S). This study aimed to screen the loci associated with S risk in …

[HTML][HTML] Immunoregulatory potential of pregnancy-specific β1-glycoprotein

VP Timganova, MS Bochkova, MB Rayev… - Медицинская …, 2021 - cyberleninka.ru
The embryo, being half an antigenically “foreign” organism, should elicit a maternal immune
response. During evolution, however, the mechanisms ensuring successful development of …

Иммунорегуляторный потенциал трофобластического β1-гликопротеина

ВП Тимганова, МС Бочкова, МБ Раев… - Медицинская …, 2021 - mimmun.ru
Аннотация Эмбрион, являясь наполовину «чужеродным» в антигенном отношении
организмом, должен вызывать ответную реакцию иммунной системы матери. Однако в …

Effect of pregnancy specific β1-glycoprotein on the replicative potential of naïve T cells and immune memory T cells

VP Timganova, LS Litvinova, KA Yurova… - Bulletin of Experimental …, 2021 - Springer
We studied the effects of pregnancy-specific β1-glycoprotein (PSG) on the replicative
potential of naïve T cells (CD45RA+) and immune memory T cells (CD45R0+) in vitro by …

Human placental organoids as a model to probe early gestation maternal immune dynamics

EM Slaby, E Brown, MW Becker, N Hansen, R Sharma… - bioRxiv, 2024 - biorxiv.org
During pregnancy, the human placenta establishes tolerance toward fetal allogeneic tissue,
where specialized trophoblast subtypes play a complex role in local and peripheral …