Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …

Reactive oxygen species (ROS) have been regarded as inevitable harmful by-products of
aerobic metabolism. Growing evidence, however, suggests that ROS play important …

Protein structure and function can be altered by reactive oxygen species produced either by
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …

Ochratoxin A (OTA), mainly produced by Aspergillus and Penicillum species, is one of the
most important mycotoxin contaminants in agricultural products. It is detrimental to human …

Saccharomyces cerevisiae Yap1 protein is an AP1-like transcription factor involved in the
regulation of the oxidative stress response. An ortholog of Yap1, MoAP1, was recently …

Hemibiotrophic plant pathogens first establish a biotrophic interaction with the host plant and
later switch to a destructive necrotrophic lifestyle. Studies of biotrophic pathogens have …

Iron, an essential element for almost every organism, serves as a regulatory signal for the
expression of virulence determinants in many prokaryotic and eukaryotic pathogens. Using …

The ability of a fungal pathogen to cause disease requires the ability to survive in the host.
Survival in the host is dependent on evasion of the host's immune system, including the …

Yeast ATP-binding cassette (ABC) proteins are implicated in many biological phenomena,
often acting at crossroads of vital cellular processes. Their functions encompass peptide …

Background Microbes must sense environmental stresses, transduce these signals and
mount protective responses to survive in hostile environments. In this study we have tested …