A review: The antiviral activity of cyclic peptides
In the design and development of therapeutic agents, macromolecules with restricted
structures have stronger competitive edges than linear biological entities since cyclization …
structures have stronger competitive edges than linear biological entities since cyclization …
Envelope proteins as antiviral drug target
J Verma, N Subbarao, MS Rajala - Journal of drug targeting, 2020 - Taylor & Francis
Attachment of a virus with a specific receptor on the cell surface is the first and foremost step
in virus infection. In case of enveloped viruses, their interaction with the host cell receptor is …
in virus infection. In case of enveloped viruses, their interaction with the host cell receptor is …
Bioinformatics study of sea cucumber peptides as antibreast cancer through inhibiting the activity of overexpressed protein (EGFR, PI3K, AKT1, and CDK4)
Breast cancer is the most common type of cancer in women globally. The overexpressed
proteins, including EGFR, PI3K, AKT1, and CDK4, have a role in the growth of breast cancer …
proteins, including EGFR, PI3K, AKT1, and CDK4, have a role in the growth of breast cancer …
Computer-aided design, synthesis, and antiviral evaluation of novel acrylamides as potential inhibitors of E3-E2-E1 glycoproteins complex from chikungunya virus
GFS Passos, MGM Gomes, TM Aquino… - Pharmaceuticals, 2020 - mdpi.com
Chikungunya virus (CHIKV) causes an infectious disease characterized by inflammation and
pain of the musculoskeletal tissues accompanied by swelling in the joints and cartilage …
pain of the musculoskeletal tissues accompanied by swelling in the joints and cartilage …
Oxidative Products of Curcumin Rather Than Curcumin Bind to Helicobacter Pylori Virulence Factor VacA and Are Required to Inhibit Its Vacuolation Activity
Curcumin is a hydrophobic polyphenol derived from turmeric with potent anti-oxidant, anti-
microbial, anti-inflammatory and anti-carcinogenic effects. Curcumin is degraded into …
microbial, anti-inflammatory and anti-carcinogenic effects. Curcumin is degraded into …
Global transmission and evolutionary dynamics of the Chikungunya virus
Chikungunya virus (CHIKV) is a re-emerging pathogen of global importance. We attempted
to gain an insight into the organisation, distribution and mutational load of the virus strains …
to gain an insight into the organisation, distribution and mutational load of the virus strains …
[HTML][HTML] Computational and biological approaches in repurposing ribavirin for lung cancer treatment: Unveiling antitumorigenic strategies
Lung cancer is among leading causes of death worldwide. The five-year survival rate of this
disease is extremely low (17.8%), mainly due to difficult early diagnosis and to the limited …
disease is extremely low (17.8%), mainly due to difficult early diagnosis and to the limited …
An Overview of Indian Biomedical Research on the Chikungunya Virus with Particular Reference to Its Vaccine, an Unmet Medical Need
MM Varikkodan, F Kunnathodi, S Azmi, TY Wu - Vaccines, 2023 - mdpi.com
Chikungunya virus (CHIKV) is an infectious agent spread by mosquitos, that has
engendered endemic or epidemic outbreaks of Chikungunya fever (CHIKF) in Africa, South …
engendered endemic or epidemic outbreaks of Chikungunya fever (CHIKF) in Africa, South …
In silico identification and in vitro antiviral validation of potential inhibitors against Chikungunya virus
The Chikungunya virus (CHIKV) has become endemic in the Africa, Asia and Indian
subcontinent, with its continuous re-emergence causing a significant public health crisis …
subcontinent, with its continuous re-emergence causing a significant public health crisis …
Exploring the effect of temperature on inhibition of non-structural protease 3 of Chikungunya virus using molecular dynamics simulations and thermodynamics …
Chikungunya viral infections are creating problems in humans, therefore, there is a need to
find promising drugs to cure the patients. As of today, there is no promising and efficient drug …
find promising drugs to cure the patients. As of today, there is no promising and efficient drug …