[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

[HTML][HTML] Immunogenic cell death: an emerging target in gastrointestinal cancers

M Chiaravalli, A Spring, A Agostini, G Piro, C Carbone… - Cells, 2022 - mdpi.com
Immunogenic cell death (ICD) is a regulated form of cell death that induces the activation of
both innate and adaptive immune responses through the release of damage-associated …

Tumour‐associated neutrophils: Potential therapeutic targets in pancreatic cancer immunotherapy

Q Wu, H Mao, Z Jiang, D Tang - Immunology, 2024 - Wiley Online Library
Pancreatic cancer (PC) is a highly malignant tumour of the digestive system with poor
therapeutic response and low survival rates. Immunotherapy has rapidly developed in …

[HTML][HTML] Pancreatic Cancer Research beyond DNA Mutations

H Sato, K Sasaki, T Hara, Y Tsuji, Y Arao, C Otsuka… - Biomolecules, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is caused by genetic mutations in four genes:
KRAS proto-oncogene and GTPase (KRAS), tumor protein P53 (TP53), cyclin-dependent …

[HTML][HTML] Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia

PK Chintamaneni, SKSS Pindiprolu, SS Swain… - Cancer Letters, 2024 - Elsevier
Pancreatic cancer poses a significant challenge within the field of oncology due to its
aggressive behaviour, limited treatment choices, and unfavourable outlook. With a mere …

[HTML][HTML] Immunogenic cell death-associated biomarkers classification predicts prognosis and immunotherapy efficacy in pancreatic ductal adenocarcinoma

W Peng, J Yang, L Xia, X Qian, G Long, H Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction Immunogenic cell death (ICD) is a sort of regulated cell death (RCD) sufficient to
trigger an adaptive immunological response. According to the current findings, ICD has the …

[HTML][HTML] Unveiling the immunosuppressive landscape of pancreatic ductal adenocarcinoma: implications for innovative immunotherapy strategies

S Guo, Z Wang - Frontiers in Oncology, 2024 - frontiersin.org
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), stands as the
fourth leading cause of cancer-related deaths in the United States, marked by challenging …

Epigenetic therapeutic strategies in pancreatic cancer.

A Orlacchio, S Muzyka, TA Gonda - International Review of Cell and …, 2024 - europepmc.org
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies,
characterized by its aggressiveness and metastatic potential, with a 5-year survival rate of …