Caffeine for the pharmacological treatment of apnea of prematurity in the NICU: dose selection conundrum, therapeutic drug monitoring and genetic factors
JY Long, HL Guo, X He, YH Hu, Y Xia… - Frontiers in …, 2021 - frontiersin.org
Caffeine citrate is the drug of choice for the pharmacological treatment of apnea of
prematurity. Factors such as maturity and genetic variation contribute to the interindividual …
prematurity. Factors such as maturity and genetic variation contribute to the interindividual …
[HTML][HTML] Treating apnea of prematurity
J Pergolizzi, A Kraus, P Magnusson, F Breve, K Mitchell… - Cureus, 2022 - ncbi.nlm.nih.gov
Premature babies often suffer apnea of prematurity as a physiological consequence of an
immature respiratory system. Hypercapnia may develop, and neonates with apnea of …
immature respiratory system. Hypercapnia may develop, and neonates with apnea of …
Association between PER and CRY gene polymorphisms and the response to caffeine citrate treatment in infants with apnea of prematurity
JB Xie, W Zhuang, Y Zhu, Z Zheng, YR Huang… - Frontiers in …, 2024 - frontiersin.org
Background Circadian rhythms impact metabolism and the therapeutic effects of drugs. The
purpose of this study was to determine the association between PER and CRY …
purpose of this study was to determine the association between PER and CRY …
CRISPR gene-editing models geared toward therapy for hereditary and developmental neurological disorders
Hereditary or developmental neurological disorders (HNDs or DNDs) affect the quality of life
and contribute to the high mortality rates among neonates. Most HNDs are incurable, and …
and contribute to the high mortality rates among neonates. Most HNDs are incurable, and …
The association of gene polymorphisms of adenosine and dopamine receptors with the response to caffeine citrate treatment in infants with apnea of prematurity: a …
J Xie, W Zhuang, Y Zhu, Z Zheng, Y Huang… - Italian Journal of …, 2024 - Springer
Background To investigate the potential influence of adenosine and dopamine receptor
genes polymorphisms in combination with clinical factors on the response of preterm infants …
genes polymorphisms in combination with clinical factors on the response of preterm infants …
Recent research on gene polymorphisms related to caffeine therapy in preterm infants with apnea of prematurity.
XIE Jiang-Biao, LIN Xin-Zhu - Chinese Journal of …, 2022 - search.ebscohost.com
Apnea of prematurity (AOP) is onc of the common diseases in preterm infants. The main
cause of AOP is immature development of the respiratory control center. If AOP is not treated …
cause of AOP is immature development of the respiratory control center. If AOP is not treated …
[HTML][HTML] 咖啡因治疗早产儿呼吸暂停相关基因多态性的研究进展
谢江彪， 林新祝 - Chinese Journal of Contemporary Pediatrics, 2022 - ncbi.nlm.nih.gov
早产儿呼吸暂停（ apnea of prematurity， AOP） 是早产儿的常见疾病之一，
发病原因主要是呼吸控制中枢发育的不成熟。 AOP 如果得不到及时有效的处理会引发呼吸衰竭 …
发病原因主要是呼吸控制中枢发育的不成熟。 AOP 如果得不到及时有效的处理会引发呼吸衰竭 …