The cytoskeleton is an interconnected network that provides support and organization to
cells. In eukaryotes, its main components include actin and microtubules, two types of …

Endocytosis includes a number of processes by which cells internalize segments of their
plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis …

Cell motility is regulated by multiple processes, including cell protrusion, cell retraction, cell–
matrix adhesion, polarized exocytosis and polarized vesicle trafficking, each of which is …

Lipid droplets (LDs) are cellular organelles critical for lipid homeostasis, with intramyocyte
LD accumulation implicated in metabolic disorder-associated heart diseases. Here we …

A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Microvilli are actin-based structures found on the apical aspect of many epithelial cells. In
this review, we discuss different types of microvilli, as well as comparisons with actin-based …

Macropinocytosis is a conserved endocytic process by which cells engulf droplets of
medium into micron-sized vesicles. We use light-sheet microscopy to define an underlying …

Recent evidence implicates the actin cytoskeleton in the control of receptor signaling. This
may be of particular importance in the context of immune receptors, such as the B cell …

Members of the myosin superfamily are actin-based molecular motors that are
indispensable for cellular homeostasis. The vast functional and structural diversity of …

Myosin-I molecular motors are proposed to play various cellular roles related to membrane
dynamics and trafficking. In this Cell Science at a Glance article and the accompanying …