Development of the human placenta

MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses

N Grandi, E Tramontano - Frontiers in immunology, 2018 - frontiersin.org
About 8% of our genome is composed of sequences with viral origin, namely human
Endogenous Retroviruses (HERVs). HERVs are relics of ancient infections that affected the …

Trophoblast organoids as a model for maternal–fetal interactions during human placentation

MY Turco, L Gardner, RG Kay, RS Hamilton, M Prater… - Nature, 2018 - nature.com
The placenta is the extraembryonic organ that supports the fetus during intrauterine life.
Although placental dysfunction results in major disorders of pregnancy with immediate and …

Ovarian follicular function is not altered by SARS–CoV-2 infection or BNT162b2 mRNA COVID-19 vaccination

Y Bentov, O Beharier, A Moav-Zafrir… - Human …, 2021 - academic.oup.com
STUDY QUESTION Does the immune response to coronavirus disease 2019 (COVID-19)
infection or the BNT162b2 mRNA vaccine involve the ovarian follicle, and does it affect its …

Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation

C Lavialle, G Cornelis, A Dupressoir… - … of the Royal …, 2013 - royalsocietypublishing.org
The development of the emerging field of 'paleovirology'allows biologists to reconstruct the
evolutionary history of fossil endogenous retroviral sequences integrated within the genome …

HERV envelope proteins: physiological role and pathogenic potential in cancer and autoimmunity

N Grandi, E Tramontano - Frontiers in microbiology, 2018 - frontiersin.org
Human endogenous retroviruses (HERVs) are relics of ancient infections accounting for
about the 8% of our genome. Despite their persistence in human DNA led to the …

Virus entry: molecular mechanisms and biomedical applications

DS Dimitrov - Nature Reviews Microbiology, 2004 - nature.com
Viruses have evolved to enter cells from all three domains of life—Bacteria, Archaea and
Eukaryotes. Of more than 3,600 known viruses, hundreds can infect human cells and most of …

From ancestral infectious retroviruses to bona fide cellular genes: role of the captured syncytins in placentation

A Dupressoir, C Lavialle, T Heidmann - Placenta, 2012 - Elsevier
During their replication, infectious retroviruses insert a reverse-transcribed cDNA copy of
their genome, a “provirus”, into the genome of their host. If the infected cell belongs to the …

ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses

M Tokuyama, Y Kong, E Song… - Proceedings of the …, 2018 - National Acad Sciences
Endogenous retroviruses (ERVs) are integrated retroviral elements that make up 8% of the
human genome. However, the impact of ERVs on human health and disease is not well …

Junk DNA as an evolutionary force

C Biémont, C Vieira - Nature, 2006 - nature.com
Junk DNA as an evolutionary force | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …