Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and
growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity …

Interest in excitotoxicity expanded following its implication in the pathogenesis of ischemic
brain injury in the 1980s, but waned subsequent to the failure of N-methyl-D-aspartate …

This review provides an overview of the importance of microbiota in the regulation of gut–
brain communication in immune-related neurological disorders. The gastrointestinal (GI) …

In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are broadly expressed in
thedeveloping and adult mammalian brain. BDNF/TrkB-stimulated intracellular signaling is …

Brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) support the viability
and function of many types of neurons, and are likely mediators of activity-dependent …

▪ Abstract Despite considerable evidence that neuronal activity influences the organization
and function of circuits in the developing and adult brain, the molecular signals that translate …

Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …