[HTML][HTML] Evolving Horizons: Adenovirus Vectors' Timeless Influence on Cancer, Gene Therapy and Vaccines
PD Trivedi, BJ Byrne, M Corti - Viruses, 2023 - mdpi.com
Efficient and targeted delivery of a DNA payload is vital for developing safe gene therapy.
Owing to the recent success of commercial oncolytic vector and multiple COVID-19 …
Owing to the recent success of commercial oncolytic vector and multiple COVID-19 …
[HTML][HTML] Non-Ebola Filoviruses: Potential Threats to Global Health Security
Y Munyeku-Bazitama, F Edidi-Atani, A Takada - Viruses, 2024 - mdpi.com
Filoviruses are negative-sense single-stranded RNA viruses often associated with severe
and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality …
and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality …
A bivalent Adenovirus-Vectored Vaccine induces a robust humoral response, but does not protect cynomolgus macaques against a lethal challenge with Sudan virus
S van Tol, P Fletcher, F Feldmann… - The Journal of …, 2024 - academic.oup.com
The most recent Sudan virus (SUDV) outbreak in Uganda was first detected in September
2022 and resulted in 164 laboratory-confirmed cases and 77 deaths. There are no approved …
2022 and resulted in 164 laboratory-confirmed cases and 77 deaths. There are no approved …
Prevention and post-exposure management of occupational exposure to Ebola virus
MA Moso, CK Lim, E Williams, C Marshall… - The Lancet Infectious …, 2023 - thelancet.com
There have been significant advances in the prevention and management of Ebola virus
disease (EVD) caused by Zaire Ebola virus (ZEBOV), including the development of two …
disease (EVD) caused by Zaire Ebola virus (ZEBOV), including the development of two …
Perspectives on Advancing Countermeasures for Filovirus Disease: Report From a Multisector Meeting
A Sprecher, R Cross, A Marzi, KA Martins… - The Journal of …, 2023 - academic.oup.com
Although there are now approved treatments and vaccines for Ebola virus disease, the case
fatality rate remains unacceptably high even when patients are treated with the newly …
fatality rate remains unacceptably high even when patients are treated with the newly …
Developing a vaccine against Sudan virus disease
D Manno - The Lancet Infectious Diseases, 2023 - thelancet.com
Sudan virus causes Sudan virus disease, a severe infection similar to Ebola virus disease
and with a casefatality rate of about 55%. 1, 2 Eight known Sudan virus outbreaks have …
and with a casefatality rate of about 55%. 1, 2 Eight known Sudan virus outbreaks have …
Testing a prophylactic vaccine regimen against Ebola virus disease in Sierra Leone: vaccine safety, immunogenicity and factors affecting immunogenicity
D Manno - 2024 - researchonline.lshtm.ac.uk
BACKGROUND: In response to the 2014-16 Ebola virus disease (EVD) epidemic in West
Africa, the EBOVAC1 consortium fast-tracked the clinical development of a two-dose …
Africa, the EBOVAC1 consortium fast-tracked the clinical development of a two-dose …